Thesis and Description- Hemophilia is a hereditary disease where the body lacks certain blood clotting factors because of a defective gene. (worldbookonline.com) A hemophiliac’s blood lacks the active form of one of these factors.(worldbookonline.com) People with this disease experience excessive, or even fatal bleeding. (galegroup.com)
Number of people affected – It is estimated that 10,000 people are born with this disease. It is a lifelong and chronic illness. (google.com)
Life Expectancy- as of 2015, hemophilia was the most common coagulation factor deficiency and also had the highest associated treatment cost for a disorder. Life expectancy for people with Hemophilia is the same for regular people, because there is effective treatment. …show more content…
The other 30% develop the disorder from a spontaneous genetic mutation. In extremely rare cases hemophilia can develop after birth. (worldbook.com) This is called “acquired hemophilia.” (galegroup.com) This is the case in people whose immune system forms antibodies that attack factors VIII or IX. A boy who inherits the hemophilia on his X chromosome will be a hemophiliac. A girl who inherits the defective gene on one of her X chromosomes will be a carrier. Interestingly, she might transmit the defective gene to her children, but she won’t get the disease. (galegroup.com) They are called first-pregnancy hemophiliacs if their first child is a boy, and he inherits the disease. Boys have one X chromosome, and one Y chromosome, but girls have 2 X chromosomes, and one Y chromosome. (worldbook.com) She won’t be a hemophiliac because the normal gene on her other X chromosome provides enough of the essential clotting factor. IN extremely rare cases, a girl can actually inherit the defective gene on both X chromosomes and will be a hemophiliac. In rare cases, a hemophiliac father and a carrier mother can pass on the right combination of parental chromosomes to result in a hemophiliac female child. (worldbook.com) This is very, very, rare however, and the vs majority of hemophiliacs, either with hemophilia A or B, are …show more content…
(galegroup.com) Hemophiliacs, especially children, need to be careful while playing and exercising. (worldbook.com) most hemophiliac children will experience bruises, but when they are older will experience bleeding in muscles, which is far more painful. Hemophiliacs suffer most when internal blood vessels break, causing bleeding into areas such as the head, or joints. Leaking blood accumulates in these areas, putting pressure on the surrounding tissue and causing pain, swelling, and loss of function. (galegroup.com) Many hemophiliacs become crippled from repeated bleeding into joints. Some people believe that hemophiliacs can bleed to death from even a small external cut. However, such deaths do not occur because there is enough bleeding factor in their system to halt bleeding from the skin.
Number of people affected – It is estimated that 10,000 people are born with this disease. It is a lifelong and chronic illness. (google.com)
Life Expectancy- as of 2015, hemophilia was the most common coagulation factor deficiency and also had the highest associated treatment cost for a disorder. Life expectancy for people with Hemophilia is the same for regular people, because there is effective treatment. …show more content…
The other 30% develop the disorder from a spontaneous genetic mutation. In extremely rare cases hemophilia can develop after birth. (worldbook.com) This is called “acquired hemophilia.” (galegroup.com) This is the case in people whose immune system forms antibodies that attack factors VIII or IX. A boy who inherits the hemophilia on his X chromosome will be a hemophiliac. A girl who inherits the defective gene on one of her X chromosomes will be a carrier. Interestingly, she might transmit the defective gene to her children, but she won’t get the disease. (galegroup.com) They are called first-pregnancy hemophiliacs if their first child is a boy, and he inherits the disease. Boys have one X chromosome, and one Y chromosome, but girls have 2 X chromosomes, and one Y chromosome. (worldbook.com) She won’t be a hemophiliac because the normal gene on her other X chromosome provides enough of the essential clotting factor. IN extremely rare cases, a girl can actually inherit the defective gene on both X chromosomes and will be a hemophiliac. In rare cases, a hemophiliac father and a carrier mother can pass on the right combination of parental chromosomes to result in a hemophiliac female child. (worldbook.com) This is very, very, rare however, and the vs majority of hemophiliacs, either with hemophilia A or B, are …show more content…
(galegroup.com) Hemophiliacs, especially children, need to be careful while playing and exercising. (worldbook.com) most hemophiliac children will experience bruises, but when they are older will experience bleeding in muscles, which is far more painful. Hemophiliacs suffer most when internal blood vessels break, causing bleeding into areas such as the head, or joints. Leaking blood accumulates in these areas, putting pressure on the surrounding tissue and causing pain, swelling, and loss of function. (galegroup.com) Many hemophiliacs become crippled from repeated bleeding into joints. Some people believe that hemophiliacs can bleed to death from even a small external cut. However, such deaths do not occur because there is enough bleeding factor in their system to halt bleeding from the skin.