The serotonin framework has been generally explored in investigations of significant depresion . The innervations of the serotonin framework venture from the dorsal raphe nucleous in the brain, including the cerebral cortex and hippocampus. A pattern of diminished 5-HT1A receptors seems to be the common factor with major depression. Depression has been connected to issues with uneven characters in the brain , particularly with the neurotransmitters serotonin, norepinephrine, and dopamine. It is extremely hard to really quantify the level of neurotransmitters in a person brain and their movement. What we do know is that anti-depressant drugs that we use to treat the manifestations of depression , are known to follow up on these specific neurotransmitters
