When intense demand is placed on the muscle tissue and energy is needed in the form of atp, the Cori cycle is typically active. The Cori cycle consists of 2 main parts operating in separate areas of the body. The cells in the muscle work in conjunction with the cells in the liver to produce energy for the muscle to perform under certain conditions. The first part of the cycle, which occurs in the muscle, breaks down glucose and forms lactate through a process called glycolysis. This part generates 2 atp. The second part of the cycle, which occurs in the liver, then takes the lactate produced in the muscle and turns it back in to glucose through a process called gluconeogenesis. This part uses 6 atp. Ultimately then, there’s a loss of 4 atp
