Scheme-1-Synthesis of substituted tetrahydrocarbazole Dissolve 8.8gm (0.08mol) of cyclohexanone in 50 ml of glacial acetic acid add 8.8 gm (0.08mol) of substituted phenyl hydrazine and boil the solution under reflux for 15 min, cooled the solution, where the product was crystallised out. Filtered it with vacuum pump, then drained well and recrystallised using Ethanol.
Scheme-2: Synthesis of N-substituted Tetrahydrocarbazoles
Suspended 1 gm (0.07 mol) of substituted tetrahydrocarbazole in 20 mL of 10% NaOH solution into a well corked conical flask and add 2 mL of substituted acid chloride with constant shaking for 10 min. until the odour has disappeared and then it was cooled. Filtered and washed the synthesized N-Substituted derivative using water and recrystallized with ethanol.
Computational