Acute Lung Injury Paper

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Running head: TRANSFUSION 1 TRANSFUSION 2 Transfusion-related acute lung injury (TRALI) is an under-reported, life-threatening complication of blood component transfusion due to the misinterpretation of symptoms, unfamiliarity of causes, and delay of standardizing methods of prevention. According to Mazzei, Popovsky, & Kopko (2008, 734), TRALI is characterized by symptoms indistinguishable from acute respiratory distress syndrome (ARDS) and usually consists of some or all of the following symptoms: Cyanosis (bluish color of skin), dyspnea (difficulty breathing), hypotension (low blood pressure), hypoxemia (low oxygen in blood), and sometimes fever. Bux (2005, 2) agrees that x-rays and other radiological testing show patchy infiltrates in the lungs and …show more content…
C. (2013, Winter). TRALI revisited. Lab Medicine, 44(1), 33-36. DOI: 10.1309/LMHCYPRU38S7PKJN
Klein, H. G., & Anstee, D. J. (2008). Some unfavorable effects of transfusion. Mollison’s blood transfusions in clinical medicine, 11th Ed. (pp. 666-700). Oxford, UK: Blackwell Publishing, Ltd.
Mazzei, C. A., Popovsky, M. A., & Kopko, P. M. (2008). Noninfectious complications of blood transfusion. In J. D. Roback’s, M. R. Combs’s, B. J. Grossman’s, & C. D. Hillyer’s (Eds.), Technical manual, 16th Ed. (pp. 715-749). Bethesda, Maryland: AABB.
TRANSFUSION 8
Peters, A. L., van Hezel, M. E., Juffermans, N. P., & Vlaar, A. P. J. (2015, January). Pathogenesis of non-antibody mediated transfusion-related acute lung injury from bench to bedside. Blood Review, 29(1), 51-61. DOI: http://dx.doi.org/10.1016/jblre.2014.09.007
Popovsky, M. A. (2015, May). Transfusion-related acute lung injury: Three decades of progress but miles to go before we sleep. Transfusion, 55(5), 930-934. doi: 10.1111/trf.13064
Sachs, U. J. (2013). Recent insights into the mechanism of TRALI. ISBT Science Series, 8, 142-148. DOI:

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