Herpes Research Paper

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“Herpes simplex viruses types 1 and 2 (HSV-1 and HSV-2) are human neurotropic viruses that establish latent infection in dorsal root ganglia (DRG) for the entire life of the host (Steiner, I., & Benninger, F., 2013, p. 1).” Herpes is known as a sexually transmitted infection that has no known cure. This type of STI is transmitted through sexual contact and bodily fluids. People need to be aware of the types of transmission, clinical manifestations and diagnostic studies that confirm herpes is present in their body.
The common cause of the herpes infection is unprotected sexual activity. Risk factors associated with genital herpes is having multiple sex partners, not taking the proper precautions with an individual who is infected and being
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“The biology of its ability to infect the organism, evade the immune response, reactivate, and cause recurrent peripheral cutaneous disease, as well as neurological disease fueled intensive research (Steiner, I., & Benninger, F., 2013, p.5).” This type of virus is contagious and starts infecting an individual at a cellular level. The pathophysiology should be understood on how exactly this virus infects its host. “The genome is a double-stranded DNA molecule located within an icosapentahedral capsid consisting of 162 capsomers (Steiner, I., & Benninger, F., 2013, p.1).” The cell is a protein encapsulated which consists of glycoproteins, lipids as well as polyamines (Steiner, I., & Benninger, F., 2013). “After cell surface attachment, binding to gD receptor occurs, activating the membrane fusion machinery (Steiner, I., & Benninger, F., 2013, …show more content…
Usually gynecologists say there is no need to test someone unless there is an active lesion that they can swab and test for accurate diagnosis of herpes simplex two virus. “Historically, the gold standard for the diagnosis of genital herpes has been via a physical examination and direct testing of mucocutaneous lesions during an outbreak, thereby limiting the diagnosis to symptomatic individuals ( Raphaelidis, L., 2014, p.194).” Now there is evidence based research on diagnostic tests for asymptomatic individuals. Doctors can test for herpes antibodies that are present in the serum even if the patient has no clinical manifestations. The results comes down to whether that person has been exposed to either herpes simplex virus one or herpes simplex virus two. “HSV-2 IgG is a test that should not be ordered without the patient making an informed decision and understanding the potential benefits and repercussions of being tested (Raphaelidis, L., 2014, p.198).” Knowing the facts that a person is in fact infected can cause an individual great emotional harm. The person who is being tested should have all the facts before actually making a decision whether to be tested for the herpes virus or

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