Other evidence in support of the dopamine hypothesis relating to the substantia nigra include structural changes in the pars compacta. Some of the other changes in the substantia nigra include increased expression of NMDA receptors, and reduced dysbindin expression. Increased NMDA receptors may point to the involvement of glutamate-dopamine interactions in schizophrenia. Due to the changes to the substantia nigra in the schizophrenic brain, it may eventually be possible to use specific imaging techniques to detect physiological signs of schizophrenia in the substantia nigra. https://www.youtube.com/watch?v=nEnklxGAmak
Another factor that contributes to dopamine accumulation is an enzyme called MB-COMT, Membrane-bound Catechol-O-methyltransferase. …show more content…
Antabuse works by interfering with the body's ability to absorb alcohol. It inhibits production of an enzyme that would otherwise allow the body to absorb an alcohol breakdown product called acetaldehyde. This causes extremely unpleasant side effects that can include flushing, nausea, and palpitations if alcohol is ingested. Naltrexone reduces the cravings and pleasure that alcoholics receive from consumption of alcohol by blocking receptors in the brain. In clinical trials, naltrexone was shown to reduce the risk of relapse. …show more content…
Our patient Tom appears to have a well-paying job and a healthy family, but he suffers from moderate to severe anxiety. This disorder causes him to stress and he tends to over-worry about things that his anxiety tells him are a threat to his stability and way of life, finances, and health. He also suffers from physical symptoms as manifestations that are brought on by his anxiety. These symptoms have been present for about six months, and they include muscle tension, headaches, hot flashes, irritability, nausea, and fatigue. When he feels anxious, Tom has difficulty concentrating and he can’t sleep at night. At times his anxiety disorder prevents him from being able to function at his place of
Another factor that contributes to dopamine accumulation is an enzyme called MB-COMT, Membrane-bound Catechol-O-methyltransferase. …show more content…
Antabuse works by interfering with the body's ability to absorb alcohol. It inhibits production of an enzyme that would otherwise allow the body to absorb an alcohol breakdown product called acetaldehyde. This causes extremely unpleasant side effects that can include flushing, nausea, and palpitations if alcohol is ingested. Naltrexone reduces the cravings and pleasure that alcoholics receive from consumption of alcohol by blocking receptors in the brain. In clinical trials, naltrexone was shown to reduce the risk of relapse. …show more content…
Our patient Tom appears to have a well-paying job and a healthy family, but he suffers from moderate to severe anxiety. This disorder causes him to stress and he tends to over-worry about things that his anxiety tells him are a threat to his stability and way of life, finances, and health. He also suffers from physical symptoms as manifestations that are brought on by his anxiety. These symptoms have been present for about six months, and they include muscle tension, headaches, hot flashes, irritability, nausea, and fatigue. When he feels anxious, Tom has difficulty concentrating and he can’t sleep at night. At times his anxiety disorder prevents him from being able to function at his place of