St John’s Wort is a herb and its flowers and leaves are used to make medicine. It is most commonly used to treat mild to moderate depression and other symptoms that can sometimes go along with it, such as anxiety, tiredness, loss of appetite and trouble sleeping. Other conditions that St. John’s Wort has been used for are heart palpitations, premenstrual syndrome (PMS), menopause, attention deficit-hyperactivity disorder (ADHD), obsessive-compulsive disorder (OCD), and seasonal affective disorder (SAD). It has also been used to help treat exhaustion, fibromyalgia, chronic fatigue syndrome (CFS), migraine and other types of headaches, muscle pain, nerve pain, and irritable bowel syndrome (IBS). It has been used as a smoking cessation adjunct
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It is also composed of common plant constituents such as volatile oil, xanthone derivatives, flavonoids, biapigenin, amentoflavone, and flavonoid derivatives, which may have antidepressant effects but have not been researched extensively.
Lawvere, S., & Mahoney, M. C. (2006). St John’s Wort: American Family Physician. Retrieved October 10, 2015 from …show more content…
represents the evidence is suggestive of higher effectiveness rate for St. John’s Wort compared with a placebo, and similar effectiveness against current antidepressant medication with fewer common side effects or less severity in side effects. (Linde, K., et al (2008) Conclusion)
There is a controversy in the data which in one article states it has a higher effective rate on major depression than placebo, yet the article posted by the Journal of the American Medical Association suggests that it has only slightly higher effectiveness on minor depression similar to that of a placebo. The data produced through these trials is inconsistent with the data from the first article using a sample size of 336 patients they found the research did not support the usage of St. John’s Wort for major depression. (Davidson, J., et al (2002) Results)
The third article by BioMed Central was conducted with a double-blind, and placebo-controlled study. The conclusion of this study was consistent with the conclusion found by Linde, K., Berner, MM., & Kriston, L. being that St. John’s Wort was more effective and safer than the placebo, but had similar effectiveness to the current standard medication used for depression. (Kasper, S., et al (2006)
It is also composed of common plant constituents such as volatile oil, xanthone derivatives, flavonoids, biapigenin, amentoflavone, and flavonoid derivatives, which may have antidepressant effects but have not been researched extensively.
Lawvere, S., & Mahoney, M. C. (2006). St John’s Wort: American Family Physician. Retrieved October 10, 2015 from …show more content…
represents the evidence is suggestive of higher effectiveness rate for St. John’s Wort compared with a placebo, and similar effectiveness against current antidepressant medication with fewer common side effects or less severity in side effects. (Linde, K., et al (2008) Conclusion)
There is a controversy in the data which in one article states it has a higher effective rate on major depression than placebo, yet the article posted by the Journal of the American Medical Association suggests that it has only slightly higher effectiveness on minor depression similar to that of a placebo. The data produced through these trials is inconsistent with the data from the first article using a sample size of 336 patients they found the research did not support the usage of St. John’s Wort for major depression. (Davidson, J., et al (2002) Results)
The third article by BioMed Central was conducted with a double-blind, and placebo-controlled study. The conclusion of this study was consistent with the conclusion found by Linde, K., Berner, MM., & Kriston, L. being that St. John’s Wort was more effective and safer than the placebo, but had similar effectiveness to the current standard medication used for depression. (Kasper, S., et al (2006)