The spleen removes old and injured erythrocytes from the circulation and also removes cellular debris and killed microorganisms [85, 86]. The spleen is the only lymphoid organ that filters the blood (the rest filter lymph), it contains the largest single aggregate of lymphoid tissue in the body [91]. If bacteria are resistant to oxidation or evade killing by erythrocytes because of other reasons, the liver and the spleen both kill and digest bacteria. . However, too many living bacteria may overload the liver and spleen, causing their enlargement and injuries [52].
Thus, bactericidal cells of cardiovascular compartment include erythrocytes, the liver’s Kuppfer cells and the macrophages of spleen lymphoid tissue. Erythrocytes kill bacteria,
Thus, bactericidal cells of cardiovascular compartment include erythrocytes, the liver’s Kuppfer cells and the macrophages of spleen lymphoid tissue. Erythrocytes kill bacteria,