Exposure to these chemicals is imminent because they can be found anywhere in the environment. As a result, the effects of exposure to genotoxic chemicals have always been of great interest due to the linkage of exposure to these chemicals and cancer. It has been proven that exposure to genotoxic chemicals damages DNA and it has also been hypothesized that prolonged exposure could even result in cancer. In order to determine whether a chemical with suspected genotoxic effects does damage DNA, the frequency of sister chromatid exchange has been used. Sister chromatid exchange is a sensitive biomarker for detecting genotoxic chemicals. Sister chromatid exchange is an S-phase DNA-repair process that symmetrically exchanges genetic material between the two identical sister chromatids [7]. When DNA is damaged, the frequency of sister chromatid exchange is higher and it can be inferred that the chemical the individual was exposed to has genotoxic
Exposure to these chemicals is imminent because they can be found anywhere in the environment. As a result, the effects of exposure to genotoxic chemicals have always been of great interest due to the linkage of exposure to these chemicals and cancer. It has been proven that exposure to genotoxic chemicals damages DNA and it has also been hypothesized that prolonged exposure could even result in cancer. In order to determine whether a chemical with suspected genotoxic effects does damage DNA, the frequency of sister chromatid exchange has been used. Sister chromatid exchange is a sensitive biomarker for detecting genotoxic chemicals. Sister chromatid exchange is an S-phase DNA-repair process that symmetrically exchanges genetic material between the two identical sister chromatids [7]. When DNA is damaged, the frequency of sister chromatid exchange is higher and it can be inferred that the chemical the individual was exposed to has genotoxic