Sickle Cell Disease Research Paper

Improved Essays
More than 80,000 Americans have been struggling with Sickle Cell Disease (Bennett). Including 1 in 375 African-Americans. When I first heard this number, it was shocking to me. I thought sickle cell was a really rare disease. But then I did the research and found out more. Sickle cell disease (SCD) is an inherited blood disorder that affects red blood cells, causing them to change the normal disc shape to a sickle shape (Bennett). Sickle Cell Disease Association of America estimates that 70,000 to 100,000 individuals have SCD and 3 million individuals have the sickle cell trait (Terrie). Totally not rare at all. Sickle Cell Disease is an disease that affects many people and comes with many dangers, pain, treatments and possible cures. …show more content…
Unfortunately, pain linked to SCD goes treated the wrong way many times. The most common sites for pain include the thigh, hip, knee, abdomen, chest, and lower back (Terrie). Symptoms of SCD also include: fatigue, jaundice (yellowing of the skin), shortness of breath, pain in body organs or joints, pain in body organs or joints, and many more (Bennett). While several drugs have been studied as potential treatments for SCD, In 1998, the FDA approved hydroxyurea for us in symptomatic SCD patients (Terrie). The first question I had when I first learned about sickle cell was, “Is there a cure?”, and I looked up exactly …show more content…
It’s good to diagnose SCD at an early age, after birth even if possible. This lets doctors attack the disease early, letting the child live a more normal life than patients who have to deal with it all their lives. “It’s becoming clear that it is highly important that children with SCD are seen at the earliest possible moment after they are delivered and the diagnosis is made and that they are followed aggressively in the first three to five years of life, particularly to ensure that we minimize the number of very severe events that could occur in those first five years of life,” says Dr. John Cunningham, section chief of pediatric hematology/oncology at the University of Chicago

Related Documents

  • Improved Essays

    Chi Square Test Lab Report

    • 2147 Words
    • 9 Pages

    Sickle cell disease is an inherited disorder that is caused by a mutation in the DNA sequences that codes for the beta chain of the hemoglobin protein. Red blood cells are, normally, flexible and round, but with the sickle cell anemia the red blood cells become sticky, rigid, and crescent shaped. The Hemoglobin protein carries oxygen in the red blood cells throughout the body. With the disease, the blood cell’s shape can cause them to get lodged in the blood vessels resulting in the obstruction of blood flow, especially in the smaller arterial vessels in the body This occurrence not only reduces oxygen content to the area of concern, but can be a very painful experience for the victim. People who inherit this disease have two abnormal hemoglobin…

    • 2147 Words
    • 9 Pages
    Improved Essays
  • Improved Essays

    I am in support of the “Sickle Cell Disease Research, Surveillance, Prevention, and Treatment Act of 2015.” Sickle Cell is a serious blood disorder that causes red blood cells to become misshaped. These abnormally shaped red blood cells can get clustered into blood vessels and block blood flow to areas of the body. According to the center of disease and control the number of people with sickle cell in the united states is unknown, but it is prevalent amongst African-Americans occurring in 1 out of 365 births.…

    • 800 Words
    • 4 Pages
    Improved Essays
  • Improved Essays

    Cells with sickle cell disease are hard and easily stick to each other. When the cells lose their oxygen, they take on the shape of a sickle or crescent. The cells stickiness can block small blood vessels and the flow of normal oxygen-carrying blood. This can cause varying levels of pain. According to sicklecelldisease.org, normal red blood cells can live up to 120 days.…

    • 656 Words
    • 3 Pages
    Improved Essays
  • Great Essays

    Sickle Cell Trait Essay

    • 1570 Words
    • 7 Pages

    Sickle Cell Trait Twila S. Russell Virginia College NUR 2320 Professor Deandrala Huffman October 24, 2016 Sickle Cell Trait According to the National Center on Birth Defects and Developmental Disorders, “Sickle Cell Trait (SCT) affects 1 in 12 Blacks or African Americans in the United States and about 1 out of every 100 Latinos has sickle cell trait.” (CDC.gov). SCT occurs when a person inherits a gene for sickle beta globin from one parent and a gene for normal beta-globin from the other parent. This means the person won’t have sickle cell disease, but will be a trait “carrier” and can pass it on to their children (CDC.gov).…

    • 1570 Words
    • 7 Pages
    Great Essays
  • Improved Essays

    Sickle cell disease is a major health burden in the Indian community. It contributes to millions of deaths worldwide however it is most prevalent in tribal populations in the rural sectors of India. “Sickle cell disease or SCD is an inherited abnormality of the red blood cell characterized by chronic haemolytic anemia with numerous clinical consequences” (Ugwu 87). The shape of hemoglobin, which gives red blood cells their color is turned from an oval to a crescent shape when the sickle cell gene is present. The sickle shaped cells cause blockage of capillaries which leads to many symptoms such as chronic pain, pneumonia, severe anemia, and increased risk for infections (Powars 1).…

    • 1228 Words
    • 5 Pages
    Improved Essays
  • Great Essays

    With someone that has SCD, there spleen doesn’t work very good at all and sometimes it doesn’t work. Because of this reason, it makes it really easy for that organ to become heavily infected and infections for somebody who is affected by sickle cell anemia isn’t good at…

    • 749 Words
    • 3 Pages
    Great Essays
  • Improved Essays

    Pain crisis is the primary symptom of SCD; it is caused by sticky, sickle cells forming blood clots resulting in ischemia. Acute chest syndrome is a potentially life-threatening complication that occurs when blood clots collect in the small blood vessels that supply the lungs. Symptoms include fever, chest pain, dyspnea, chills, and hemoptysis. Pulmonary infiltrates are common as well as pulmonary hypertension, and the majority of patients are hypoxemic (Paul, Castro, Aggarwal, & Oneal, 2011). Splenic sequestration is another common complication; rising when the sickle cells become clogged and are trapped in the spleen causing rapid splenomegaly and pain (National Heart, Lung and Blood Institute, 2015).…

    • 1703 Words
    • 7 Pages
    Improved Essays
  • Improved Essays

    Sickle Cell Research Paper

    • 1293 Words
    • 6 Pages

    The most common problem is the sickle cell shaped red blood cells that get stuck to the blood vessels, blocking blood flow, in results causing certain conditions. One condition is Hand-Foot syndrome, which is, when the foot and hand have pain, swelling and fever. Another condition is “sickle cell crisis”, this is a painful symptom that a person experience sudden body, organ and joint pain. This is due to when the sickle blood cells block oxygen flow to the tissues. This crisis can last a few minutes to weeks causing the patient to be hospitalized.…

    • 1293 Words
    • 6 Pages
    Improved Essays
  • Improved Essays

    This is a disease that gets worse with time, treatments only help lessen complications or prevent them. Treatment options for people vary depending on how bad their condition is. A stem cell transplant would essentially cure a person with the disease, most people do not meet the qualifications for a transplant and even at that, the procedure is still very risky. Usually the first symptom people with Sickle Cell experience, one of the least severe, is swelling in their feet and hands, caused by blockage in the blood vessels. To treat the swelling, pain medicine is usually prescribed and a doctor will recommend an increase in fluids, drink more water.…

    • 903 Words
    • 4 Pages
    Improved Essays
  • Improved Essays

    Identify one intervention that can be taken by the RN to reduce the stigma and improve management of acute and chronic pain associated with Sickle Cell Disease, (SCD). One intervention that comes to my mind after reading the articles would be recognizing the cues to an acute pain episode and responding appropriately and in a timely manner (Jenerette & Ataga, 2014). By doing so, it could help manage the chronic pain associated with sickle cell disease. Patients with SCD are often stigmatized as addicted to opioids, disbelieved or mistrusted regarding reports of pain and not being allowed to participate in their own health care (Jenerette & Ataga, 2014).…

    • 279 Words
    • 2 Pages
    Improved Essays
  • Improved Essays

    Sickle cell crisis is an acute condition of sickle cell anemia. Sickle cell anemia is a genetic condition. Both parents must be carriers of the gene in order for a baby to be born with sickle cell anemia. In the United States, the gene predominantly affects black people of African decent. Sickle cell anemia is a disease where there is an inadequate number of healthy red blood cell throughout the body.…

    • 932 Words
    • 4 Pages
    Improved Essays
  • Improved Essays

    Sickle Cell Research Paper

    • 1038 Words
    • 5 Pages

    Scientist are continuing to prevail in finding treatments and they have been able to find new experimental treatments that can help reduce the pain of sickle cell anemia. These experimental treatments include gene therapy, nitric oxide, statins, and drugs to help boost fetal hemoglobin blood cell…

    • 1038 Words
    • 5 Pages
    Improved Essays
  • Improved Essays

    Special delivery of toxic cell-free heme causes vascular damage in Sickle Cell Disease Scientists describe a novel mechanism responsible for blood vessel injury in Sickle Cell Disease (SCD): microparticles derived from sickle cells deliver heme to the vascular endothelial cells causing oxidative damage. Sickle Cell Disease (SCD) is an inherited blood disorder caused by a single base mutation in the DNA of affected patients, producing abnormal hemoglobin molecules. In SCD, red blood cells (RBCs) that carry oxygen lose their flexibility and typical round shape, and become rigid with a distinctive “sickle” shape that make their passage through blood vessels more difficult. Millions of people worldwide suffer from SCD; this is also the most…

    • 720 Words
    • 3 Pages
    Improved Essays
  • Improved Essays

    The signs and symptoms of SCD can vary greatly from person to person, even within the same family and can change over time. Major features and symptoms of sickle cell anemia may include: painful swelling of the hands and feet, known as dactylitis, anemia, frequent infections, vision problems, and severe occurrences of…

    • 1506 Words
    • 7 Pages
    Improved Essays
  • Superior Essays

    Essay On Sickle Cell

    • 1260 Words
    • 6 Pages

    People who have sickle cell trait will not any symptoms. Individuals that have the disease pass the down gene down to their children (Mayo Clinic…

    • 1260 Words
    • 6 Pages
    Superior Essays