Research Paper On Thalidomide

Decent Essays
Thalidomide
Sold under the brand name Immunoprin, among others, is an immunomodulatory medicate and the model of the thalidomide class of medications. Today, thalidomide is utilized chiefly as a treatment of specific tumors (different myeloma) and of an intricacy of sickness.
Thalidomide causes birth surrenders The FDA and other administrative organizations have endorsed showcasing of the medication just with an auditable hazard assessment and alleviation methodology that guarantees that individuals utilizing the medication know about the dangers and stay away from pregnancy; this applies to men and ladies both, as the medication can be transmitted in sperm.
There is a high hazard that thalidomide can cause over the top blood clusters. There

Related Documents

  • Improved Essays

    Minoxidil Research Paper

    • 398 Words
    • 2 Pages

    Minoxidil, an antihypertensive vasodilator medication, which was developed in the 1950’s by a company called Upjohn originally used to treat ulcers. During their experiments with dogs, they figured out that it did not cure ulcers, but acted as a vasodilator. Due to this recent discovery, Upjohn was able to develop a compound called Minoxidil in 1963 as well as being able to synthesize over 200 variations of the compound. The molecular structure and compound of Minoxidil is C9H15N50, made entirely of nonmetals with the molecular weight being 209.2483 g/mol, the UIPAC name being 3 hydroxy, 2 imino, 6 piperidin, 1 ylpyrimidin, and 4 amine. The percentage composition of carbon being 51.65, hydrogen being 7.24, nitrogen being 33.47, and oxygen being 7.64.…

    • 398 Words
    • 2 Pages
    Improved Essays
  • Improved Essays

    Fentanyl Research Paper

    • 864 Words
    • 4 Pages

    Fentanyl According to Susan Robertson, the drug fentanyl which is an opiate agonist, has been around since the 1960s and created by Dr. Paul Jansen. "The use of fentanyl as a pain reliever and anesthetic was quickly adopted in the medical setting. In the 1960s, the agent was introduced as an intravenous anesthetic under the brand name Sublimaze"(S.Robertson)pg.1. In the 90s fentanyl was turned into a patch which breaks down into the blood stream through a period of 72 hours.…

    • 864 Words
    • 4 Pages
    Improved Essays
  • Improved Essays

    Research Paper On Xanax

    • 695 Words
    • 3 Pages

    Xanax Samantha E. Mendoza San Joaquin Valley College Xanax The brand name is Xanax, the generic name is alprazolam, and the chemical name is 8-Chloro-1-methyl-6-phenyl-4H-s-triazolo [4,3-α] [1,4] benzodiazepine. It is a drug used for managing anxiety disorder or for the short term relief of anxiety symptoms in adults (WebMD, n.d.). Xanax is considered a Schedule IV narcotic because Xanax has a medical use, but the drug is still considered to have potential for abuse. It belongs to a class of medications called benzodiazepines, which are a type of medications commonly known as tranquilizers (Addiction blog, n.d.).…

    • 695 Words
    • 3 Pages
    Improved Essays
  • Superior Essays

    Utilization Of Alteplase

    • 1301 Words
    • 6 Pages

    Background Information Alteplase is a serine protease which has the property of fibrin-enhanced conversion of plasminogen to plasmin. Alteplase binds to fibrin in a thrombus and converts the entrapped plasminogen to plasmin initiating local fibrinolysis with minimal systemic effects. Alteplase is cleared rapidly from circulating plasma with an initial half-life of less than 5 minutes and the clearance is mediated primarily by the liver. Alteplase indications include the management of acute ischemic stroke in adults for improving neurological recovery and reducing the incidence of disability. Treatment should be initiated within 3 hours after the onset of stroke symptoms, and after exclusion of intracranial hemorrhage by a cranial computerized…

    • 1301 Words
    • 6 Pages
    Superior Essays
  • Improved Essays

    Thalidomide is a sedative created in the 1950s by a West German pharmaceutical company called Chemie Gruenenthal. Originally it was produced to treat morning sickness, and was used a lot by pregnant women. It was advertised to be safe for both mother and child, because as they tested Thalidomide on rats nothing happened to them, no matter how big the dose of Thalidomide was they got. It was the new wonder drug and sold for 4 years in 46 countries across the world until it got pulled from the market in November 1961 due to its teratogenic effects on the fetus.…

    • 612 Words
    • 3 Pages
    Improved Essays
  • Improved Essays

    Adverse events of drugs may be reported as side effects, treatment effects, toxicity etc. (Zorzela 2014; Loke 2011; (Higgins 2011).)(For this review I will consider them all.) The adverse events of Methotrexate are related to body weight especially if more than one dose is used. These are- (Pfeifer 2013;Elson 2016;Hajenius 2009;Song 2016) . Treatment side effects Drug side effects…

    • 783 Words
    • 4 Pages
    Improved Essays
  • Decent Essays

    Prescription medications are one of the many options available to help overcome depression in patients. There are many advantages along with disadvantages that come with pharmaceutical treatment of depression. The use of Anti-depressants is one of the many options available for patients to help manage their depression. Along with many advantages, antidepressants have many adverse reactions and risks associated with them. Besides the use of drugs to treat depression, there are many other lasting ways with no side effects which can help patients deal with depression.…

    • 184 Words
    • 1 Pages
    Decent Essays
  • Improved Essays

    Hello National Institute of Health, As you may know, Thalidomide can be a life-saving drug in certain cases such as Cancer and Leprosy however, this is only done in the case of absolute emergencies due to the very serious side effects it causes such as limb malformation and birth defects. The reason Thalidomide can simultaneously have such positive and negative effects will make more sense once we understand the mechanism for the acid hydrolysis of thalidomide. Initially thalidomide will be protonated via H3O+ at the double bonded oxygen which is between the protonated nitrogen and the stereo center. As we know this results in a positive charge on the oxygen.…

    • 606 Words
    • 3 Pages
    Improved Essays
  • Improved Essays

    1960s Thalidomide Scare

    • 1072 Words
    • 5 Pages

    Frances Kesley, the FDA agent who was in charge of reviewing William S. Merrell, Inc.’s application to market thalidomide in the US, is regarded as a national hero whose reluctance to accept the company’s assurances of safety saved the country from experiencing the full force of the “thalidomide scare” that Europe faced during the 1960s (Daemmrich 2004). Suspicious that the drug had not been tested for teratogenicity Kesley demanded that rigorous testing be done on the drug (The New York Times, 2013). Merrell removed their application in 1962 after the “Thalidomide Scare” attained widespread media coverage for its effects overseas (Daemmrich 2004). Since then, most nations across the globe have strictly limited or banned thalidomide. In cases when the prescription of thalidomide is inevitable to treat cancer and leprosy, the Food and Drug Administration has put together an elaborate plan that doctors are supposed to enact when prescribing thalidomide to patients.…

    • 1072 Words
    • 5 Pages
    Improved Essays
  • Improved Essays

    Adderall Research Paper

    • 817 Words
    • 4 Pages

    Adderall is combination drug of stimulants, amphetamine and dextroamphetamine, which are used in this medicine to treat people with Attention Deficit/ Hyperactive Disorder (ADD/ADHD). It is a total treatment plan for psychological and social disorders and other treatments. Adderall may help to increase the ability to pay attention, concentrate, stay focused and stop moving so frequently. Like any other thing or medicine, too much is never good. People should only take certain medicines if and only if they are diagnosed with a disorder or disease and they are given a prescription for a medicine to treat them.…

    • 817 Words
    • 4 Pages
    Improved Essays
  • Decent Essays

    1. Thalidomide is a drug that can be used to treat insomnia, nauseas during pregnancy, certain cancers, ulcers in AIDS patients, and leprosy. The controversy regarding thalidomide is that it causes some pretty severe birth defects. The drug first came out in the 1950s and was wildly used in Europe. However, in the US its use was stopped by Frances Kelsey of the FDA.…

    • 225 Words
    • 1 Pages
    Decent Essays
  • Improved Essays

    OTC Drugs Research Paper

    • 440 Words
    • 2 Pages

    In our general public today, the utilization of legitimate medications, for example, liquor, tobacco, and OTC medications are being utilized at a disturbing rate. The media mortar charming pictures for all to see as a worthy piece of regular daily existence. For instance, surely understood mixed drink organizations publicize in ways that depict their items as fun and a typical piece of regular daily existence, by the utilization of engaging pictures of superb creatures and infectious trademarks. OTC medications organizations additionally utilize a wide range of media roads to elevate their items to people in general, which presents them as broadly acknowledged and typical for cheerful, sound way of life. Lamentably, a number of Americans get to be distinctly dependent on these lawful medications and the result is not glad or sound, it is by and large exceptionally dangerous.…

    • 440 Words
    • 2 Pages
    Improved Essays
  • Superior Essays

    Effects on Mothers This disease can cause many issues amongst the mothers whose child has NAS. Often times people just look at the effects that NAS has on the baby but the drug-abusing mother is also effected. Women have been using prescription and some nonprescription drugs while pregnant and letting themselves get an addiction for them. In (14) . . .…

    • 1875 Words
    • 8 Pages
    Superior Essays
  • Improved Essays

    Would you take a drug that would relieve you of pregnancy sickness, even if it meant your baby would have birth defects? I definitely would not! This happened when mothers took Thalidomide. Thalidomide is a sedative drug that was prescribed to pregnant women to help cure their morning sickness. It wasn’t until years later that they realized Thalidomide’s harmful effects.…

    • 466 Words
    • 2 Pages
    Improved Essays
  • Great Essays

    They wanted to see if they would produce the same human disorders. They gave a pregnant rat and bunny 2 an half pills of Thalidomide and watched for the results. What they discover was nothing, both rats and bunnies were fine. They found no problems with the fetus, but what they could conclude when Thalidomide could hurt their newborn baby (ebscohost). The studies gave them that the drug effects would happen between days 35 through 50.…

    • 1297 Words
    • 6 Pages
    Great Essays