Research Paper On Paget's Disease

Paget’s Disease Paget’s disease is the breakdown of bone in an abnormal fashion, which then leads to bone forming abnormally. Bones naturally break down and new tissue is formed, this is called renewal. The disease disrupts the renewal process, and creates abnormalities. The abnormalities usually include enlargement and weakening of bones. The symptoms of this disease include many things, and the most reported symptom is bone pain. Other symptoms include joint stiffness, visible deformities of the bones, bones easily fracture, and warm skin over affected area. The major areas that are targeted by the disease are the pelvis, skull, spine, and legs. The cause of this disease is unknown, but is currently being studied by scientists. They believe it is linked with genetics. Bones continuously break down and rebuild themselves. When the rate is normal, bones are rebuilt strong. It is known that the disease leads to bones breaking down at a much faster than it can rebuild itself, therefore disrupting the bone rebuilding process. Due to the bone decomposition at this faster rate, the new bone being produced is softer and weaker. The softer …show more content…
X-rays can find abnormalities on bones such as enlargement. The bone scans, are more invasive because radioactive material is injected into bones, and the more materials travel to where the bone is infected with this disease and can easily be spotted on the scans. The treatment for the disease is typically medication. The medications used for treatment are also used for the treatment are biphosphates, and are also used to treat osteoporosis. Some people that have less severe cases of the disease may not require treatment at all but must be monitored to make sure the disease does not worsen. In extremely severe cases orthopedic surgery may be needed to correct severe bone abnormalities. These extreme cases are rare, but have a long-term effect on the