Procalcitonin

Decent Essays
Sepsis and its consequences are one of the leading causes of death in Intensive care units (ICUs)[1, 2]. Prompt diagnosis and administration of appropriate antimicrobial therapy are essential for reducing complications associated with sepsis-related organ failure. However, sepsis response is complex and not all patients with infections display related signs or symptoms. The early detection of those patients showing an initial unfavorable course or with an increased mortality risk is essential in order to prevent the progression of organ dysfunction, which would increase the frequency of complications and patient mortality.
Procalcitonin (PCT), the 116 amino acid precursor of calcitonin, is abnormally elevated in sepsis. Procalcitonin has been

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