Pharmacologic Response Paper

Treatment Sadly, despite the complexity and multiple risk factors associated with the condition, no universal recommendations for treatment exist (Smith, 2014). Rather than a single treatment modality most practitioners utilize a symptoms approach. This idea proposes that troublesome symptoms dictate treatment. While effective, this may not be the best course of action to prevent disease progression. Another school of thought is to treat the underlying cause of the symptoms and promote significant lifestyle changes to help decrease comorbidities. Whatever the course of treatment, there is one major question practitioners need to ask patients: what are your fertility plans? This questions helps practitioners better guide treatment. Below are two treatment plans, one for those desiring pregnancy and one for those not.
Plan A- Non-pregnancy Most published research utilizes a symptoms approach addressing each troublesome …show more content…
Menstrual dysfunction is made worse by weight gain and many patients experience amenorrhea with clinical obesity. One of the major recommendations is lifestyle modification alongside pharmacologic intervention. Important to note is the need to readdress pharmacologic response once a patient has lost 10% or greater of their body weight. Those patients with probable insulin resistance may also benefit from the use of metformin to regulate menstruation. Many patients tolerate large doses poorly due to their gastrointestinal effects. For these patients using a taper system to gradually increase their dose over a six week period may provide increased adherence. Metformin has been shown to regulate patient’s cycles after three months of continuous, but only in those patients with insulin resistance (Wahab, 2012). Sanoee (2011) posited that metformin may also help with hyperandrogenism although there is little evidence to support