PCOS Research Paper

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Many adults, children, and adolescents are obese, which is a worldwide problem. Obesity can manifest other diseases and disorders. Obesity in adolescents can manifest problems for their health in the future. Polycystic ovary syndrome (PCOS) is a dysfunction disorder of the ovaries. PCOS is characterized by high concentrations of androgen, metabolic abnormalities, and metabolic syndrome (MetS). PCOS is an endocrine disorder in females and affects about 15% of women in their reproductive age. Those with PCOS have an increased risk of cardiovascular disease (CVD). PCOS affects women’s fertility, and it can also affect the women’s mental health. PCOS typically emerges during the adolescent years of women. PCOS is a common syndrome, affecting 18.5-26% of adolescent girls. The risk of PCOS increases among those who are obese, and the risk is elevated among obese adolescents. Not all women with PCOS are overweight. The article shows the correlation between obesity and PCOS. The clinical symptoms of PCOS are oligoanovulation (OAV), hirustism, acne, alopecia, acanthosis nigricans, and increased visceral fat deposition. Typically, women with PCOS show lower levels of sex hormone-binding gobulin (SHBG) and increased levels of free circulating testosterone (cFT), luteinizing hormone (LH) to …show more content…
Weight loss greatly improves the risk of cardiovascular disease associated with PCOS. A sample of 59 obese girls with PCOS aged 12-19 years of age, 26 girls who reduced their weight after 1 year, decreased cFT, insulin concentrations, and homeostatic model assessment, and increased SHBG concentrations. The main challenge is to maintain the weight loss. Pharmacological treatment is another option to reduce PCOS symptoms. Oral contraceptives and insulin sensitizers are effective for adolescents with PCOS in combination of lifestyle intervention or when lifestyle intervention

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