Osteitis Fibrosa Cystica is a condition that is associated with excessive parathyroid hormone production (hyperparathyroidism), in which bone tissue becomes soft and deformed. Treatment is directed toward the underlying parathyroid condition and relieving any bone pain. Before 1950, about half of people diagnosed with hyperparathyroidism had Osteitis Fibrosa. Now it is uncommon, probably because patients with hyperparathyroidism are diagnosed earlier, before this complication has occurred. OFC was discovered by Friedrich Daniel von Recklinghausen in 1890.
Too much parathyroid hormone (hyperparathyroidism) can lead to increased bone breakdown, which can cause bones to become weaker and more fragile. Many people with hyperthyroidism develop osteoporosis. Not all bones respond to PTH in the same way. Some develop abnormal areas where the bone is very soft and has almost no calcium in it. This …show more content…
The first bones to be affected are the fingers, facial bones, ribs, and pelvis. Long bones, which are longer than they are wide, are also among the first affected. As the disease progresses, any bone may be affected.
OFC could be diagnosed using varieties of techniques. Patient’s afflicted muscles with OFC, either appear unaffected or “bulked up”. Muscular symptoms appear upon the onset of hyperparathyroidism, they are generally sluggish contracting and relaxing the muscles.
To treat Osteitis Fibrosa Cystica, most of the bone problems from Osteitis Fibrosa can be reversed with surgery to remove the abnormal parathyroid glands. However, some people may choose to not have surgery, and instead be followed with blood tests and bone
Too much parathyroid hormone (hyperparathyroidism) can lead to increased bone breakdown, which can cause bones to become weaker and more fragile. Many people with hyperthyroidism develop osteoporosis. Not all bones respond to PTH in the same way. Some develop abnormal areas where the bone is very soft and has almost no calcium in it. This …show more content…
The first bones to be affected are the fingers, facial bones, ribs, and pelvis. Long bones, which are longer than they are wide, are also among the first affected. As the disease progresses, any bone may be affected.
OFC could be diagnosed using varieties of techniques. Patient’s afflicted muscles with OFC, either appear unaffected or “bulked up”. Muscular symptoms appear upon the onset of hyperparathyroidism, they are generally sluggish contracting and relaxing the muscles.
To treat Osteitis Fibrosa Cystica, most of the bone problems from Osteitis Fibrosa can be reversed with surgery to remove the abnormal parathyroid glands. However, some people may choose to not have surgery, and instead be followed with blood tests and bone