A genome-wide association study scans hundreds of thousands of genetic markers across thousands of individuals’ complete sets of DNA to find gene variations that may be related to a particular disease. The researchers indicated that these studies can be used to find gene variations that play a role in common, complex diseases such as obesity. The researchers also specified that often, a change in just one small section of the DNA that encodes for a gene can make a difference in the gene’s action. These tiny DNA variations, called “gene variants” or “single-nucleotide polymorphisms” (SNPs), are often related to disease risk. In the case of obesity researchers at the Peninsula Medical school used genome-wide association studies to identify the first obesity-related gene variants in the so-called “fat mass and obesity-associated” also referred to as the FTO gene on chromosome 16. The
A genome-wide association study scans hundreds of thousands of genetic markers across thousands of individuals’ complete sets of DNA to find gene variations that may be related to a particular disease. The researchers indicated that these studies can be used to find gene variations that play a role in common, complex diseases such as obesity. The researchers also specified that often, a change in just one small section of the DNA that encodes for a gene can make a difference in the gene’s action. These tiny DNA variations, called “gene variants” or “single-nucleotide polymorphisms” (SNPs), are often related to disease risk. In the case of obesity researchers at the Peninsula Medical school used genome-wide association studies to identify the first obesity-related gene variants in the so-called “fat mass and obesity-associated” also referred to as the FTO gene on chromosome 16. The