During the last years of the twentieth century, the United Nations declared "Decade of the brain", and at the beginning of the XXI century theoretical understanding of the pathogenesis of affective disorders and mechanisms of therapeutic action of antidepressant drugs has undergone a significant evolution. This was due to the rapid development of ultramicroscopic, neurophysiological, neyrogistohimicheskih and molecular-genetic methods of studying the structure and in vitro brain functions (in certain nerve cells in the brain tissue culture), with the introduction of non-invasive neuroimaging techniques (X-ray computed tomography - CT, magnetic resonance imaging - MRI, magnetic resonance spectroscopy, and functional MRI - fMRI, SPECT - OFET or the SPECT, positron emission tomography - PET) in order to clearly see and quantify many parameters lifetime structure, local blood flow and brain metabolism in health and disease, as well as studies using experimental models and affective disorders in vivo (in animal behavior).
Thanks to this new technology has been proven that when a number of psychiatric …show more content…
neuroplasticity (see reviews: R.Duman, 2002; B.McEwen et al, 2002; M.Yu.Drobizhev, A.F.Iznak 2003; J.-P.Olie, J.-P.Macher, J.. .Costa e Silva, 2004). The term is relatively new to psychiatry, it has long been used in cognitive neuroscience to describe rearrangements (mostly functional) organization neural network, developing in the training underlying memory (E.Kendel, 1980; B.I.Kotlyar, 1986), and neurology and neurosurgery (V.V.Semchenko, 1994; GN Kryzhanovsky, 2001; E.I.Gusev, P.R.Kamchatnov, 2004) - to describe the processes of recovery (at least partial) of certain brain functions after the organic CNS damage (as a result of stroke, traumatic brain injury,
Thanks to this new technology has been proven that when a number of psychiatric …show more content…
neuroplasticity (see reviews: R.Duman, 2002; B.McEwen et al, 2002; M.Yu.Drobizhev, A.F.Iznak 2003; J.-P.Olie, J.-P.Macher, J.. .Costa e Silva, 2004). The term is relatively new to psychiatry, it has long been used in cognitive neuroscience to describe rearrangements (mostly functional) organization neural network, developing in the training underlying memory (E.Kendel, 1980; B.I.Kotlyar, 1986), and neurology and neurosurgery (V.V.Semchenko, 1994; GN Kryzhanovsky, 2001; E.I.Gusev, P.R.Kamchatnov, 2004) - to describe the processes of recovery (at least partial) of certain brain functions after the organic CNS damage (as a result of stroke, traumatic brain injury,