II) Immunological diagnosis:
These methods are sensitive and specific, and useful in confirming the diagnosis (Bergquist, 1990). These tests are all time consuming and require a laboratory well equipped with proper instruments and trained persons (Xiang et al., 2003).
Detection of circulating Antigens for Diagnosis of Schistosomiasis:
Van Dam et al. (2004), developed reagent strip for the diagnosis of schistosomiasis. It was based on parasite antigen detection in urine of infected people. The test …show more content…
It can be differentiating current from past infection and can be used for detection of viable organisms after chemotherapy (Stoker, 1990). It can be used to study parasitic drug resistance, as well as to evaluate the effect of new drugs and re-evaluate old ones (Stoker, 1990).
III) Indirect methods for schistosomiasis diagnosis:-
Rectal snips can be done to obtain a rapid diagnosis of schistosomiasis or if screening tests have been inconclusive, by taking several small samples of rectal (not anal) mucosa using a curette and a proctoscope. Both S.mansoni and S. haematobium eggs can be identified (Blanchard, 2004).
Treatment
Praziquantel is the drug of choice for schistosomiasis; it is most effective against adult worm of all Schistosomiasis species. For travelers, the therapy should be at least 6-8 weeks after last contact to the contaminated fresh water. There is an evidence of parasitic resistance to praziquantel has been reported with low cure rates in recently exposed or heavily infected populations (Doenhoff et al.,