Menopause is an inevitable stage in life that every woman goes through with varying symptoms. Some symptoms such as vasomotor instability can significantly affect women’s quality of life. Approximately 80% of women experience VMS during the menopausal transition (MT) and most consider them as moderate to severe. VMS is associated with increased bone turnover, consequently leading to osteoporosis, as well as increased risk of cardiovascular diseases. As VMS are caused by sudden discontinuation of estrogen provision, hormone replacement therapy (HRT) seems to be the most relevant treatment option (Abdi, et al., 2016). I am glad you to see you are researching on HRT and I am looking forward to reading your project. Previously HRT were associated
