Skin is the largest organ in our body that serves a lot of important functions. Firstly, it acts as a protective barrier against mechanical injury, loss of body fluids, chemicals, particles, microbes and UV radiation. [1] It also provides sensation for touch, temperature, pressure and pain. [1] Besides, it allows mobility by providing a surface for grip. [1] It also has a role in homeostasis of body temperature. [1] Next, it is involved in production of vitamin D, and has an immunity function too. [1] By conducting examination of the skin, we can identify several primary and vascular skin lesions. A skin lesion is a superficial growth or patch of the skin that does not resemble the area surrounding it. [4] Skin lesions can be grouped into primary
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It is the abnormal growth of skin cells, most often develops on skin exposed to the sun and also occur on areas of your skin not ordinarily exposed to sunlight. [9] There are several signs of malignant changes can be observed. Malignant skin lesion has changes in size, changes in color, can be multicolor, has irregular border, has erosion or sore, has bleeding and does not heal. [1] The three common malignancies afflicting the skin are squamous cell carcinoma, basal cell carcinoma and malignant melanoma. Squamous cell carcinoma is the malignancy of keratinocytes. [1] They are usually found on sun exposed areas, particularly the scalp, ears, lips, and hands of fair-skinned adults over 60. [1] They are a faster growing malignancy than the basal cell carcinoma and can metastasize. [1] Basal cell carcinomas are a slowly growing malignancy that rarely metastasizes. [1] They are usually found on sun- exposed areas, particularly the face and commonly in between the nose and ears, in fair-skinned adults over 40. [1] Melanoma is a skin neoplasm arising from the malignant degeneration of melanocytes. [10] It is classically subdivided in four types. They are superficial spreading melanoma, nodular melanoma, lentigo maligna melanoma and acral lentiginous melanoma. …show more content…
Firstly, erythema nodosum is associated with sarcoidosis, tuberculosis, post-streptococcal infection and connective tissue diseases. [1] The clinical symptoms presented are cough and sputum, breathlessness as well as sore throat. [1] Secondly, pyoderma gangrenosum is associated with ulcerative colitis, rheumatoid arthritis and leukaemia. [1] The clinical symptoms presented are rectal bleeding and joint symptoms. [1] Thirdly, dermatitis herpetiformis is associated with gluten enteropathy and it presents with changes in bowel habits. [1] Next, generalized purpura is associated with thrombocytopenic purpura and other haematological disorders. [1] It can be idiopathic and presents with haematuria, fever and weight loss. [1] Lastly, dermatitis artefacta is associated with personality disorders and the clinical symptoms are stress or anxieties.
It is the abnormal growth of skin cells, most often develops on skin exposed to the sun and also occur on areas of your skin not ordinarily exposed to sunlight. [9] There are several signs of malignant changes can be observed. Malignant skin lesion has changes in size, changes in color, can be multicolor, has irregular border, has erosion or sore, has bleeding and does not heal. [1] The three common malignancies afflicting the skin are squamous cell carcinoma, basal cell carcinoma and malignant melanoma. Squamous cell carcinoma is the malignancy of keratinocytes. [1] They are usually found on sun exposed areas, particularly the scalp, ears, lips, and hands of fair-skinned adults over 60. [1] They are a faster growing malignancy than the basal cell carcinoma and can metastasize. [1] Basal cell carcinomas are a slowly growing malignancy that rarely metastasizes. [1] They are usually found on sun- exposed areas, particularly the face and commonly in between the nose and ears, in fair-skinned adults over 40. [1] Melanoma is a skin neoplasm arising from the malignant degeneration of melanocytes. [10] It is classically subdivided in four types. They are superficial spreading melanoma, nodular melanoma, lentigo maligna melanoma and acral lentiginous melanoma. …show more content…
Firstly, erythema nodosum is associated with sarcoidosis, tuberculosis, post-streptococcal infection and connective tissue diseases. [1] The clinical symptoms presented are cough and sputum, breathlessness as well as sore throat. [1] Secondly, pyoderma gangrenosum is associated with ulcerative colitis, rheumatoid arthritis and leukaemia. [1] The clinical symptoms presented are rectal bleeding and joint symptoms. [1] Thirdly, dermatitis herpetiformis is associated with gluten enteropathy and it presents with changes in bowel habits. [1] Next, generalized purpura is associated with thrombocytopenic purpura and other haematological disorders. [1] It can be idiopathic and presents with haematuria, fever and weight loss. [1] Lastly, dermatitis artefacta is associated with personality disorders and the clinical symptoms are stress or anxieties.