An rCHI model used a traditional impact system to deliver physical impact to the head of an animal. Compared to first modification called closed-skull TBI, no craniotomy is needed in this model. It induces mTBIs ranging from mild to moderate similar to those experienced by humans by adjusting impact parameters. Loss of consciousness (LOC) defined as a decrease in breathing rate or transient termination of breathing can be observed immediately after an impact. The period of LOC is used as a sign of injury degree.
Although there is no single animal model that is entirely successful in reproducing the complete spectrum of pathological changes observed after concussion, rCHI provides an easy and accurate method of investigating the effects and
Although there is no single animal model that is entirely successful in reproducing the complete spectrum of pathological changes observed after concussion, rCHI provides an easy and accurate method of investigating the effects and