Locked-In Syndrome: A Case Study

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Description of Research
Any injury or damage to your brain can result in devastating motor or cognitive lost. The extent of this lost typically depends on the amount of damage caused and the point of injury. After receiving a brain injury, the most severe form of motor disability someone can have is Locked-in syndrome (LIS) (Pistoia et al., 2016). “It is the consequence of ventral brainstem damage as a result of vascular or traumatic lesions disconnecting corticospinal and corticobulbar tracts bilaterally” (Pistoia et al., 2016, p. 32). Locked-in syndrome causes complete paralysis with the exception of eye movement, however the patient is completely conscious and aware of surroundings (Pistoia et al., 2016). According to Pistoia et al., (2016), due to the disconnection of the cortex and spinal cord in
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The aim of this study is to investigate the presence of structural cortical changes following brainstem damage in patients with Locked-in syndrome (Pistoia et al., 2016).
Methods
All patients admitted to the Post-Coma Rehabilitation Care Unit of the San Raffaele Hospital within a two-year period were included in the study. The criteria the had to be met to be participate in the study was; diagnosis of Locked-in syndrome upon admission resulting from consequence of ventral brainstem damage of traumatic or vascular origin, at least 18 years of age, and informed consent by proxy or surrogate. Criteria that excluded patients from the study was; instability of general clinical conditions after two weeks from
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Due to the fact that the patients are conscious, preforming an adequate cognitive assessment would help reinforce data from

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