Insulin was discovered in year 1921 by Banting and Best after a lot of controversy over it, for patients suffering from Diabetes Mellitus (DM) [1]. Islets were described by Paul Langerhans, a German medical scientist but couldn’t correlate any function for them. Crystalline Insulin was prepared by John Jacob Abel of Johns Hopkins University in 1926. Later in 1950, Frederick Sanger determined the molecular structure of Insulin for which he was awarded with a Nobel Prize. In today’s era, Genetic Engineering has made possible to generate insulin in unlimited quantities but to make human insulin we need insulin of other species with modification [2].Isletin (a crude form of pancreatic extract) was recognized by Banting. James Collip, a chemist
