Infantile nystagmus syndrome (INS) may be further classified into sensory and motor types. In patients with sensory type, there is a recognizable structural abnormality leading to decreased vision while in motor type, structural abnormalities are typically absent. Affected patients often have decreased visual function even though they may have near normal visual acuity. 1, 2 The intensity of nystagmus often has a reverse correlation …show more content…
Seven (58.3%) cases had infantile motor nystagmus and 5 patients (41.7%) had sensory problems including optic nerve hypoplasia (n=3) and macular hypoplasia secondary to oculocutaneous albinism (n=2). Mean spherical refractive error before and after surgery was -2.16 ± 1.36 and -0.1 ± 0.35, respectively, mean spherical equivalent was -2.82 ± 1.65 and -0.26 ± 0.25, and mean astigmatism before and after surgery was -1.33 ± 1.14 and -0.31 ± 0.51, respectively (P<0.001 for all parameters). None of the patients required enhancement surgery and epithelial healing was uneventful in all cases. No complications were observed after PRK.
Significant improvement in both monocular and binocular best corrected visual acuities was observed after surgery. Mean monocular VA improved from 20/42 before surgery to 20/32 and mean binocular VA from 20/39 to 20/28 (Table 1 represents these data in LogMAR).
Significant improvements were observed in contrast sensitivity at three frequencies of 3, 6 and 12 Hertz (Table 2 and Figure 1).
All videonystagmographic indices were decreased significantly after surgery (Table 3 and Figure 2). Interestingly, there was not even one case in which the nystagmus intensity remain unchanged or increased after