1) Ductal carcinoma in situ (DCIS): also known as intraductal carcinoma is considered noninvasive or pre-invasive breast cancer, DCIS means a malignant proliferation of epithelial cells, confined to the lumen of ducts.
In situ carcinomas were divided into three grades: comedocarcinoma has been placed in grade 3. Solid, cribriform and micropapillary carcinomas were designated as grade 1 and classified as grade 2 if they had intermediate cytomorphology. (54)
Comedocarcinoma: is grossly, thick walled ducts filled with