1. a) Heroin is an illegal drug which is highly addictive.
b) Steroid is a drug used by athletes to make them perform better.
c) Statin is a medical drug which is used to reduce cholesterol levels.
2. a) What is the purpose of the Phase 1 trial?
The drug should pass laboratory first. This is to check if they are toxic and if they could treat disease. After that they will be tested on cells and whole organs to see how they react on chemicals. After that a drug will be tested on animals, to find out how it would work on a whole living organism. This would predict how the drug might behave in humans.
b) Suggest why in Phase 2 patients were asked to record how they felt after taking the PainGo2?
Phase2 is when a very low doses tested are on human volunteers in clinical trials. Volunteers will be asked to record how they felt after taking PainGo2 to check for side effects, and to see if is safe and effective before conducting bigger clinical trials with the optimum dose of the drug.
c) What is a placebo?
A placebo is a substance or other kind of treatment that looks just like a regular …show more content…
Because they sense more than enough dopamine, neurons may begin to reduce the number of dopamine receptors or simply make less dopamine. The result is less dopamine signalling in the brain, what the scientists call “down regulation.” Because some drugs are toxic, some neurons also may die. As a result, dopamine’s ability to activate circuits to cause pleasure is severely weakened. The person feels flat, lifeless, and depressed. In fact, without drugs, life may seem joyless. Now the person needs drugs just to bring dopamine levels up to normal. Larger amounts of the drug are needed to create a dopamine flood, or “high”—an effect known as “tolerance.”These brain changes drive a person to seek out and use drugs compulsively, despite negative
b) Steroid is a drug used by athletes to make them perform better.
c) Statin is a medical drug which is used to reduce cholesterol levels.
2. a) What is the purpose of the Phase 1 trial?
The drug should pass laboratory first. This is to check if they are toxic and if they could treat disease. After that they will be tested on cells and whole organs to see how they react on chemicals. After that a drug will be tested on animals, to find out how it would work on a whole living organism. This would predict how the drug might behave in humans.
b) Suggest why in Phase 2 patients were asked to record how they felt after taking the PainGo2?
Phase2 is when a very low doses tested are on human volunteers in clinical trials. Volunteers will be asked to record how they felt after taking PainGo2 to check for side effects, and to see if is safe and effective before conducting bigger clinical trials with the optimum dose of the drug.
c) What is a placebo?
A placebo is a substance or other kind of treatment that looks just like a regular …show more content…
Because they sense more than enough dopamine, neurons may begin to reduce the number of dopamine receptors or simply make less dopamine. The result is less dopamine signalling in the brain, what the scientists call “down regulation.” Because some drugs are toxic, some neurons also may die. As a result, dopamine’s ability to activate circuits to cause pleasure is severely weakened. The person feels flat, lifeless, and depressed. In fact, without drugs, life may seem joyless. Now the person needs drugs just to bring dopamine levels up to normal. Larger amounts of the drug are needed to create a dopamine flood, or “high”—an effect known as “tolerance.”These brain changes drive a person to seek out and use drugs compulsively, despite negative