Facts of the Case: A golfer with Klippel-Trenaunay-Weber Syndrome wanted to enter into a tournament and requested an accommodation to use a golf cart during the third round that was denied. Under Title III of the American with Disabilities Act, public businesses must provide accommodations and make modifications for people with disabilities, unless that accommodation would “fundamentally alter the nature” of the business. Casey Martin’s lawyers argued that, by Title III of the ADA, the Q-School golf tour competition cannot deny Martin equal access and must give him reasonable accommodations. They stated that golf courses are a public accommodation, and that the golf tour and qualifying rounds fall under Title III’s coverage. Using a golf cart during the third round would not “fundamentally alter the…
Zollinger-Ellison Syndrome (ZES) is a condition in which one or more tumors form in the pancreas or duodenum. The tumors which are called gastrinomas secrete large amounts of the hormone gastrin. The hormone gastrin causes the stomach to produce too much acid which then leads to peptic ulcers. Zollinger- Ellison Syndrome was first described in 1955 by two gentlemen Zollinger and Ellison.…
Goodpasture’s Syndrome, also known as Goodpasture’s Disease, antiglomerular basement antibody disease, or anti-GBM disease is an autoimmune disease affecting the lungs and kidneys. In this rare disease antibodies are formed that attack the collagen in the lungs and kidneys leading to kidney failure and bleeding in the lungs. The laboratory plays an important role in the diagnostic process of Goodpasture’s disease. Patients will experience edema, joint pain, changes of urine color, and electrolyte imbalances in the blood. Goodpasture’s Disease is treatable with steroids, different blood products, immunosuppressants, and has a good prognosis if diagnosed early.…
Muckle-Wells syndrome (MWS) is a rare genetic disorder that causes hive-like skin rashes, chills, fever, partial or total hearing loss, swollen joints, loss of kidney function, and can eventually lead to amyloidosis in some patients. Muckle-Wells syndrome is named after Thomas J. Muckle and Michael V. Wells who first described the disease in April of 1962 [1]. Muckle-Wells is in a family of diseases called Cryopyrin-Associated Autoinflammatory Syndromes (CAPS) which all are related because they are caused by a deficiency in the NLRP3 gene which is what codes for the protein Cryopyrin [2,3]. People tend to start showing symptoms as early as infancy or early childhood, and affects them for their entire lives, and if not treated can cause death…
This is a disease in which the hemoglobin protein is produced incorrectly and the red blood cells have a sickle shape. A person that is homozygous recessive for the sickle cell trait will have sickled red blood cells that all have the incorrect hemoglobin. A person who is homozygous dominant will have normal red blood cells. From the images on the first page in the packet, this trait is an example of incomplete dominance, as a person who is heterozygous for the sickle cell trait will have some misshapen cells and some normal cells. From the results, this was the case for the…
Chris Theodorakis had a bad disease that prevented him from doing certain things. One of the only things he could do was to watch birds. Now, he is able to move around (Out of the wheelchair) And go to different places and discover new birds. He even had one named after him.…
MELAS is an uncommon hereditary disorder that can cause strokes and dementia. MELAS syndrome is a neurodegenerative disorder. MELAS stands for mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes. MELAS syndrome is brought about by changes in genetic material (DNA) in the mitochondria. Our DNA is found mostly in the cell nucleus.…
I believe that there would be a ton of complications with this type of transplant. For example, one would have to consider whether or not the brain of the patient would be able to control (create homeostasis) with the body of the donor since the brain controls the regulation of hormones and nervous system. Another thing to consider would be is could connection of the patient's spinal cord and the donors spinal cord be done successfully? In the article, Russian man volunteers for first human head transplant, a man that suffers from Werdnig-Hoffmann Disease (fatal genetic disorder that breaks down muscles and kills nerve cells in the brain and spinal cord that help the body move) has volunteered to be the first canidate in the experimental elective surgery.…
The amygdala is often called the “aggression center” of the brain. There are two of them in one’s limbic system, and they are located on either side of the thalamus, at the end of the hippocampus, a little bit in front of the brain stem. When the amygdalas are stimulated, one feels anger, violence, fear, and anxiety. When the amygdalas are completely destroyed, a person has what is called Kluver-Bucy syndrome. The effects of this syndrome include hyperorality, hypersexuality, and disinhibited behavior (when a person doesn’t think through his or her actions).…
Pseudomelanosis gastri and duodeni is a rare endoscopic mucosal finding, characterized by the accumulation of iron in macrophages of the lamina propria of the stomach and duodenum. The clinical significance and long term sequelae have not been clarified. However, this benign condition is associated with a variety of clinical conditions, such as essential hypertension, chronic renal failure, diabetes mellitus, long term intake of iron supplements and furosemide. Pseudomelanosis duodeni appears to be more common than pseudo melanosis gastri given the fact that a few cases of psuedomelanosis gastri have been reported in the literature so far. We report a case of 88 year old lady with ESRD who is maintained on hemodialysis and presented with abdominal…
Final Research Project: Cotard’s Syndrome Background: I was first introduced to Cotard’s Syndrome when it grabbed my attention when I read Anil Ananthaswamy’s book titled The Man Who Wasn’t There. The stories that were described in his book allowed me to gain an inside look on people with this rare disorder that ruins one’s perception of self. Cotard’s Syndrome or Cotard Delusion is a mental illness that leaves the patient believing that they are, in broad terms, dead. They may feel like they don’t exist or never existed, are missing organs or parts of their body, are putrefying, and paradoxically are immortal. These delusions can lead the patient to dying of starvation like the first recorded case made by Jules Cotard or they can soon overcome…
The disease is genetically inherited and is a recessive. To be exhibited in…
Synpolydactyly, autism, pure hair and nail ectodermal dysplasia syndrome, and ovarian cancer are all linked to HOX gene mutations. HOX genes were first recognized through mutations in fruit flies. Mo Costandi comments in her article The Role…
Oculocutaneous Albinism I have oculocutaneous albinism which is an inherited disorder characterized by a reduction or complete lack of melanin pigment in the hair, skin and eyes. These conditions are caused by mutations in specific genes that are necessary for the production of melanin pigment in specialized cells called melanocytes which are found in your skin and eyes. Oculocutaneous albinism is inherited as an autosomal recessive genetic condition. I was diagnosed when I was three months old.…
As a result of stigma experience, PWMD’s daily living area and social network shrunk. This occurred not only due to the direct influence of being physically restrained and being avoided by others, but also due to the indirect influence of stigma experience mediated by PWMD’s behavioral change, worsened relationship between PWMD and others, and protective restriction from families. After being negatively treated, PWMD “closed off to anybody” and distanced themselves from others by themselves. For a girl with a mental disorder, “going out sometimes is like an obstacle” because she became “afraid of people’s judgments.” Another indirect influence were found in the way families treated PWMD.…