Hemophilia is a bleeding disorder in which blood doesn’t clot normally and results in excessive bleeding. The Jews were the first to recognize hemophilia and was described in the Talmud, which is a collection of Jewish writings, and stated that if two brothers had died after getting circumcised the next male baby from that family didn’t have to go through the procedure. Years later in 1803 a physician named Dr. John Conrad Otto in Philadelphia discovered that the disease was hereditary and particularly affected boys. In the 1900’s people didn’t know how to store blood so people with hemophilia received it straight after a family member had drawn blood and many people with hemophilia lived up to age thirteen. Finally in 1960 hemophilia …show more content…
Hemophilia is a disease that is inherited, meaning it often runs families. All humans have two chromosomes determining their gender XX for females and XY for males and because the disorder is only carried on the X chromosomes males are affected the most. Since males only have one X chromosome and females have two X chromosomes, one from both parents, they’ll typically have one normal X chromosome, they’ll be unaffected by this disorder since it is a recessive disease and instead will only become a carrier. It’s rare for a female to be affected by hemophilia and this situation can only occur if her father has hemophilia and her mother is a …show more content…
1 in 4,000 to 1 in 5,000 males are born with hemophilia type A and 1 in 20,000 males are born with hemophilia type B but 75% of the people with this disorder around the world have no access to treatment. Hemophilia became known as the royal disease because Queen Victoria was a carrier and passed it on to her daughters and they became carriers as well and since royal families were married within their families the hemophilia gene affected many of the family members. The most famous family member with hemophilia was Alexis, whose parents were Czar Nicholas II and Queen Victoria’s granddaughter Alexandra, who was a carrier and had passed the disease to her