2. Most Likely Diagnosis (Guillain-Barré Syndrome)
a. Expand upon your most likely diagnoses (#1 from your list above).
i. Define the pathological condition, disease or syndrome. (Make sure you include a reference for your definition).
“Guillain-Barré syndrome is a serious health problem that occurs when the body's defense (immune) system mistakenly attacks part of the nervous system. This leads to nerve inflammation that causes muscle weakness or paralysis and other symptoms.”
(Walling 2013.) In other words, GBS is an autoimmune response leading to ascending muscle weakness and paralysis. ii. Explain why the pathology is a possibility for this patient.
1. Why do the clinical manifestations this patient has make you consider the pathophysiological …show more content…
Explain each clinical manifestation or abnormal finding in the case with a reason for why it matters in the diagnosis you are considering. Explain the relationship of these signs and symptoms to the pathophysiology
General Malaise/Fatigue/Inability to sleep/Weight Loss:
Nausea/Vomiting:
Fever:
Tenderness in lower back:
Pain in lower back:
Weakness and hypoactive reflexes:
3. What other information would you need to know to help with this diagnosis?
CSF Fluid Analysis from Spinal Puncture, Nerve Conduction Studies, Basic Metabolic Panel, Spinal Cord MRI for possible spinal cord compression, EKG, Pulmonary function tests. When was his last drink of alcohol? (Guillain-Barre syndrome 2015) iii. Emphasize and discuss the pathophysiology of this diagnosis.
1. What causes it?
a. 70% of cases are caused by some sort of infection or gastroenteritis causes by food poisoning, although the exact cause or nature is unknown. (Blum 2014)
2. How does it develop?
a. It develops after usual acquiring of respiratory or GI infection, which leads to an immune/autoimmune reaction that’s aimed at the PNS, leading to lower back pain, weakness in the extremities, as well as other previously discusses symptoms. (Guillain-Barre syndrome …show more content…
Central Nervous System
c. Musculoskeletal System
d. Gastrointestinal System
e. Genitourinary System
f. Cardiovascular System
g. Respiratory System
5. How are normal anatomy and physiology altered?
a. Ascending paralysis occurs. This makes it impossible for the normal body motion to occur, as well as respiratory, GI, and GU issues. (Guillain-Barre syndrome 2015)
6. How is normal body function compromised?
a. Ascending paralysis causes weakness or loss of function of muscle function, leading to urinary incontinence and weakness in the back and extremities. Respiratory function is also compromised in time, and may cause dysphagia, and loss of tendon reflexes. (Guillain-Barre syndrome 2015)
7. What are the potential complication or sequelae of the disease process?
a. Complications of GBS could include respiratory failure and other lung illness, blood closts, permanent paralysis, and bone and muscle deformities. (Guillain-Barre syndrome 2015) iv. Who is at risk for developing this pathological condition?
People who have had any number of infections including influenza, GI illness, mycoplasma pneumonia, HIV, Herpes simplex, Mononucleosis, people with lowered immune responses following surgery, or people with Lupus of Hodgkins
a. Expand upon your most likely diagnoses (#1 from your list above).
i. Define the pathological condition, disease or syndrome. (Make sure you include a reference for your definition).
“Guillain-Barré syndrome is a serious health problem that occurs when the body's defense (immune) system mistakenly attacks part of the nervous system. This leads to nerve inflammation that causes muscle weakness or paralysis and other symptoms.”
(Walling 2013.) In other words, GBS is an autoimmune response leading to ascending muscle weakness and paralysis. ii. Explain why the pathology is a possibility for this patient.
1. Why do the clinical manifestations this patient has make you consider the pathophysiological …show more content…
Explain each clinical manifestation or abnormal finding in the case with a reason for why it matters in the diagnosis you are considering. Explain the relationship of these signs and symptoms to the pathophysiology
General Malaise/Fatigue/Inability to sleep/Weight Loss:
Nausea/Vomiting:
Fever:
Tenderness in lower back:
Pain in lower back:
Weakness and hypoactive reflexes:
3. What other information would you need to know to help with this diagnosis?
CSF Fluid Analysis from Spinal Puncture, Nerve Conduction Studies, Basic Metabolic Panel, Spinal Cord MRI for possible spinal cord compression, EKG, Pulmonary function tests. When was his last drink of alcohol? (Guillain-Barre syndrome 2015) iii. Emphasize and discuss the pathophysiology of this diagnosis.
1. What causes it?
a. 70% of cases are caused by some sort of infection or gastroenteritis causes by food poisoning, although the exact cause or nature is unknown. (Blum 2014)
2. How does it develop?
a. It develops after usual acquiring of respiratory or GI infection, which leads to an immune/autoimmune reaction that’s aimed at the PNS, leading to lower back pain, weakness in the extremities, as well as other previously discusses symptoms. (Guillain-Barre syndrome …show more content…
Central Nervous System
c. Musculoskeletal System
d. Gastrointestinal System
e. Genitourinary System
f. Cardiovascular System
g. Respiratory System
5. How are normal anatomy and physiology altered?
a. Ascending paralysis occurs. This makes it impossible for the normal body motion to occur, as well as respiratory, GI, and GU issues. (Guillain-Barre syndrome 2015)
6. How is normal body function compromised?
a. Ascending paralysis causes weakness or loss of function of muscle function, leading to urinary incontinence and weakness in the back and extremities. Respiratory function is also compromised in time, and may cause dysphagia, and loss of tendon reflexes. (Guillain-Barre syndrome 2015)
7. What are the potential complication or sequelae of the disease process?
a. Complications of GBS could include respiratory failure and other lung illness, blood closts, permanent paralysis, and bone and muscle deformities. (Guillain-Barre syndrome 2015) iv. Who is at risk for developing this pathological condition?
People who have had any number of infections including influenza, GI illness, mycoplasma pneumonia, HIV, Herpes simplex, Mononucleosis, people with lowered immune responses following surgery, or people with Lupus of Hodgkins