2. Knowledgeable - Shkreli can read the stock market very well, and knows how to make money and stay relevant.
3. Unethical – While his way of making money definitely works, he makes money by exploiting people with sicknesses that have no alternative
4. Machiavellian - He has a specific plan that he is executing for the sole purpose of self-gain.
5. Despicable - This one is common sense, anyone who thinks that it is okay to pray on the sick for the purpose of self gain is deplorable.