The study consisted of five treatment groups, these groups were divided out as follows. Glucosamine solo, chondroitin sulfate solo, a mixture of glucosamine and chondroitin sulfate, celecoxib which is an anti-inflammatory drug, and an inactive substance that looks like the study substance which in medical terms is known as a placebo. Glucosamine and chondroitin sulfate and the sequence of the two were correlated with the placebo to assess whether any of these control groups improved joint pain. Celecoxib, which requires a prescription, has been known to manage osteoarthritis pain by reducing inflammation was also correlated with the placebo to check the validity of the way the study was designed. GAIT was a double-blind study, meaning the participants and the researchers didn’t know who was taking what within the five treatment groups. Participants were treated for 6 months, being assessed at the opening of the study, month 1, 2, 4, and 6. Participants were intently observed for progress of their symptoms as well as for any possible negative reactions caused by the medications. Overall 1,583 participated in the study. Participant eligibility needed to meet a few requirements; 40 years of age or older, pain within the knee, x-ray documentation as confirmation of being diagnosed with osteoarthritis, clean from glucosamine consumption for at least 12 weeks, and clean from chondroitin …show more content…
I have come to the conclusion that these products are safe for consumption under the supervision of the individual’s health care provider. Studies have been conducted on all forms of glucosamine although not extensive, they provide evidence that the supplement form of glucosamine is safe for consumption. Mixed reviews of the effects glucosamine has on pain management of osteoarthritis and degenerative joint disease present a concern though. Be mindful and do your research prior to purchasing any glucosamine supplement. Products that consist of glucosamine and glucosamine chondroitin range a considerable amount. Some do not enclose what the label assert to, and the spectrum can vary from 25% to 115%. Some merchandise in the United States labeled glucosamine sulfate is more than likely glucosamine hydrochloride supplemented with sulfate. This merchandise is more inclined have contrasting effects than one consisting of glucosamine sulfate (WebMD,