Test–Retest Variability of Fundus-Tracked Perimetry in Open Angle Glaucoma
Introduction:
The large degree of test–retest variability with static automated perimetry (SAP) has been recognized to disease-related changes in the response characteristics of the retinal ganglion cells (RGCs). While an earlier study suggested that fixation errors had a minimal influence on the degree of variability and other studies have suggested that the interaction between fixation shifts and the spatial variation in functional loss contributes substantially to the variability observed. Fundus tracked perimetry, also known as microperimetry, is a technique that can compensate for fixation shifts through real-time visualization of the fundus. In recent years, even though fundus-tracked perimetry has been used increasingly to monitor disease …show more content…
examined the association between the measured level and local gradient of visual sensitivity on the magnitude of test–retest variability of its measurements at the peripapillary region using fundus-tracked perimetry in eyes with glaucoma.
Method:
Thirty participant with diagnosis of glaucoma with open angles on gonioscopy examination, best-corrected visual acuity (BCVA) of 6/12 or better, spherical refractive error within 6 5.00 diopters (D) and cylindrical refractive error less than 3.00 D were included in this study. All the participants underwent three examinations in one eye on fundus-tracked perimetry using a stimulus pattern that sampled the peripapillary region densely. Factors associated with the magnitude of test–retest variability at each location were examined. Statistical analysis was carried out where P< 0.001).
• Subsequent analyses were performed only between tests 1 and 2 and multivariate analyses revealed that the magnitude of test–retest variability at a given location was significantly associated with its average sensitivity and gradient of sensitivity relative to the immediately adjacent locations
Introduction:
The large degree of test–retest variability with static automated perimetry (SAP) has been recognized to disease-related changes in the response characteristics of the retinal ganglion cells (RGCs). While an earlier study suggested that fixation errors had a minimal influence on the degree of variability and other studies have suggested that the interaction between fixation shifts and the spatial variation in functional loss contributes substantially to the variability observed. Fundus tracked perimetry, also known as microperimetry, is a technique that can compensate for fixation shifts through real-time visualization of the fundus. In recent years, even though fundus-tracked perimetry has been used increasingly to monitor disease …show more content…
examined the association between the measured level and local gradient of visual sensitivity on the magnitude of test–retest variability of its measurements at the peripapillary region using fundus-tracked perimetry in eyes with glaucoma.
Method:
Thirty participant with diagnosis of glaucoma with open angles on gonioscopy examination, best-corrected visual acuity (BCVA) of 6/12 or better, spherical refractive error within 6 5.00 diopters (D) and cylindrical refractive error less than 3.00 D were included in this study. All the participants underwent three examinations in one eye on fundus-tracked perimetry using a stimulus pattern that sampled the peripapillary region densely. Factors associated with the magnitude of test–retest variability at each location were examined. Statistical analysis was carried out where P< 0.001).
• Subsequent analyses were performed only between tests 1 and 2 and multivariate analyses revealed that the magnitude of test–retest variability at a given location was significantly associated with its average sensitivity and gradient of sensitivity relative to the immediately adjacent locations