Free Radical Theory Of Aging Research Paper

The aging population are living longer in some parts of the world, and most research that have been unraveled has been guided by the free radical theory of aging. The free radical theory has provided a hypothetical plan for advance scientific work to gain more knowledge on aging. There are more than three hundred theories that could be classified into three groups.: The genetic Mutation theories, the wear and tear theories, and the cellular waste accumulation theories. Which could be divided even more into two separate groups; Such as the free radical theory of aging could fit in with characteristics of genetic mutation, as well as the cellular waste accumulation theories. This comes to show that the fact that there is a variety of theories which could be divided into groups of such depts; Only proves that there is not one theory that clearly explains aging. Recent studies have supported the free radical theory through laboratory work such as the overexpression of antioxidant enzymes resulting in increases in …show more content…
He had stated that “aging and the degenerative disease associated with it are attributed basically to the deleterious side attack of free radicals on cell constituents and on the connected tissues.” He suggested that mitochondria were key organelles involved in aging. In the 70’s Miquel’s contributed to the theory pointed out that mitochondria as sources of free radicals and DNA as a critical target to explain age associated damage in cells. With this layout, the first evidence of mitochondria were damaged inside cells and that the effects of aging on mitochondria are not due because they are more fragile and damaged upon isolation but the damage occurs in cells as they age. Which was confirmed but opened opportunities for testing to delay aging and even prevent age-associated disease by administration of antioxidants. But this was later proven wrong after experimenting and