Lansoprazole Analysis

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Table 5 Evaluation of Lansoprazole microparticles
Formulation
Code Particle size(μm) Percentage
(%) yield Entrapment efficiency
(%)
F1 181.35± 0.5 72.6±0.10 61.84±0.16
F2 200.53± 0.6 74.4±0.45 63.29±0.70
F3 221.70±1.1 77.80±0.96 64.69±0.90
F4 225.2±0.57 81.60±0.52 66.90±0.90
F5 240.72±0.8 83.52±0.56 73.35±0.46
F6 246.72±0.4 87.71±0.20 75.00±0.09
Surface morphology of the lansoprazole microspheres were shown in Figure 6. Particle surface of formulation F1 was slightly rough surface but spherically and F2 and F3 was smooth, oval and discrete. The smoothness of the surface increase which may be due to increasing ratio of polymer. Very less particulate matter of the drug were seen on the surface of the microsphere indicating uniform distribution of the drug in the …show more content…
The % cumulative release profile is given in table 9.
Table 9 in vitro dissolution study of lansoprazole tablet using phosphate buffer pH

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