Fetal Reproductive Tract Development

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Impairment of fetal reproductive tract development has profound consequences on adult health and can result in the onset of reproductive disorders during adulthood. In recent decades, considerable effort has been made to define the cellular and molecular mechanisms underlying reproductive tract development in order to better understand the fetal origins of adult reproductive disorders.
All mammals, regardless of sex, form the Wolffian and Müllerian ducts, the precursor male and female reproductive tracts, respectively, during embryogenesis; depending on sex, one primitive duct degenerates, and the other continues development. An enduring assumption in the field has been that these primitive ducts form independently of each other. Our study

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