Clinical Problem: Patients with severe Clostridium difficile that are treated with typical antibiotics have an increased chance of recurrent infection.
Objective: To determine if the use of Fecal Microbiota Transplants are more effective in treating severe cases of C diff infection. PubMed, Google scholar, and the National Center for Biotechnology Information were researched to gather clinical trial and guidelines for Fecal Microbiota Transplants. The key words used to find the evidence were, FMT, antibiotics, recurrent, and severe.
Results: The various journals evidenced that the use of FMT for the treatment of recurrent C diff was more effective than antibiotic therapy.
Conclusion: Subjects that had severe/ recurrent Clostridium difficile infection were cured quicker with the use of FMT than the subjects that received the antibiotic therapy alone. Most of the subjects that received the FMT treatment also experienced relief faster than the subjects that did not receive the transplants. Further trials should be done to have more research supporting FMT for treatment of C diff.
FECAL MICROBIOTA TRANSPLANT FOR CLOSTRIDIUM DIFFICILE
Per infection control todays Vanessa Stevens (2017) Clostridium difficile infection has been on the rise in hospitals for the past …show more content…
More than ninety percent of patients in each trial were cured from the infection with no cases of recurrence founds. With this research hospitals, can use FMT’s to treat Clostridium difficile infection and cut down on hospital acquired infection costs. The use of FMT’s can also cut down on hospital stays. More research is needed to determine the risks and how to prevent them from occurring at all. Only one or two serious adverse reactions were reported (bowel perforation and abdominal cramps) during the FMT treatment, research should focus on the risks of adverse reactions and how to prevent
Objective: To determine if the use of Fecal Microbiota Transplants are more effective in treating severe cases of C diff infection. PubMed, Google scholar, and the National Center for Biotechnology Information were researched to gather clinical trial and guidelines for Fecal Microbiota Transplants. The key words used to find the evidence were, FMT, antibiotics, recurrent, and severe.
Results: The various journals evidenced that the use of FMT for the treatment of recurrent C diff was more effective than antibiotic therapy.
Conclusion: Subjects that had severe/ recurrent Clostridium difficile infection were cured quicker with the use of FMT than the subjects that received the antibiotic therapy alone. Most of the subjects that received the FMT treatment also experienced relief faster than the subjects that did not receive the transplants. Further trials should be done to have more research supporting FMT for treatment of C diff.
FECAL MICROBIOTA TRANSPLANT FOR CLOSTRIDIUM DIFFICILE
Per infection control todays Vanessa Stevens (2017) Clostridium difficile infection has been on the rise in hospitals for the past …show more content…
More than ninety percent of patients in each trial were cured from the infection with no cases of recurrence founds. With this research hospitals, can use FMT’s to treat Clostridium difficile infection and cut down on hospital acquired infection costs. The use of FMT’s can also cut down on hospital stays. More research is needed to determine the risks and how to prevent them from occurring at all. Only one or two serious adverse reactions were reported (bowel perforation and abdominal cramps) during the FMT treatment, research should focus on the risks of adverse reactions and how to prevent