Causes Of Antimicrobial Resistance

Superior Essays
Antimicrobial resistance is gaining momentum in health care as a major cause of concern for the implications it bears on treating patients infected with microbial pathogens. Abbreviated as AMR, Antimicrobial resistance, occurs when bacteria that cause illness can no longer be treated with antibiotics (or other prescription drugs) that previously were able to inhibit the growth of or kill off the microbial infection (Frey, 2003, pg 70). For a health care provider this means treating what was once a common place infection is now a significantly more complex task. A particularly virulent infection could be untreatable by the current drugs available to health care workers (Dennis, 2014, para. 4). Analyzing the causes for the development AMR allows …show more content…
In 1952 it was discovered that penicillin resistant bacteria had existed before scientist began using penicillin as a treatment for infections (Frey, 2003, pg 70). Several of the antibiotics used today including penicillin were developed by soil microbes as a way of competing with one another for resources (Washington University, 2014, para. 5). Selective pressure within a community of bacteria is another factor leading to the development of resistance to common antibiotics. In nature the “selection” of certain bacteria occurs because only a small number of bacteria may be able to survive exposure to some antimicrobial agent. With all of the “weaker” bacteria killed the resistant bacteria grow and continue to pass down the resistance trait in their DNA (Frey, 2003, pg 70). This selective pressure relates directly to the human behavior of not finishing a complete course of antibiotics in terms of leading to the creation of resistant microbes. When a patient does not complete a course of antibiotics prescribed by a physician, and instead …show more content…
For one physicians are often guilty of overprescribing antibiotics. When antibiotics are given to a patient with a viral infection the medication will not slow the replication of the virus but it may contribute to developing resistant bacteria in the patient. Prescribing antibiotics unnecessarily may be a function of a misdiagnoses on the physicians part or a patient insisting on getting a prescription he believes will help reduces his symptoms (Frey, 2003, pg 70). Patients not finishing a complete program of antibiotics as prescribed is another form of misuse that can lead to the development of resistant strains of bacteria in the body. In recent years the growing threat of antibiotic resistant microbes had led researchers to consider taking a closer look at bacteriophage therapy as an alternative to treating infections with broad ranging antibiotics. Phage therapy was developed in the Soviet Union decades ago as way of treating bacterial infections because the trade embargo with the US prevented the soviets from acquiring adequate amounts of antibiotics (Reardon, 2004). Bacteriophages are viruses that specifically attack bacteria to treat infections by infiltrating a bacterium and causing the host to build virions instead of it’s own proteins. Eventually the build up viral material causes the bacterium

Related Documents

  • Improved Essays

    Research on healthcare-associated infections is an ongoing process and is something that microbiologists are diligently working on to find out how to stop these resistant bacteria. By finding out how these bacteria are becoming more and more resistant to outside sources we will find out how to better stop them. Through research, we have already found that it is very important for healthcare workers to wash their hands in between patients and that we carry bacteria in and on our bodies at all times. Resistant bacteria have now become a public health safety issue and any research that is being done to stop this is for the better of man-kind. It is my hope that the next major break-through in health-care associated infections is for microbiologists to find out how to kill these “superbugs” and make them less resilient in the havoc that they have been releasing on humanity.…

    • 1041 Words
    • 4 Pages
    Improved Essays
  • Improved Essays

    Infectious Diseases Society of America 's (IDSA) ultimately desires to create public policy and research activities that will salvage the damage of the overuse of antibiotics and save lives (Clinical). The GAIN act should be bolstered to make sure that antibiotics are being used appropriately (Clinical). An ‘Antibiotic Innovation and Conservation (AIC) Fee’ should be created where 75 percent of the funding should go towards the monetary funds of antibiotic development and the other 25 percent should be applied towards the funding of antimicrobial stewardship (Clinical). Public Health Antimicrobial Advisory Board (PHAAB) should recognize “priority pathogens” to pinpoint “incentives” within the Strategies to Address Antimicrobial Resistance (STAAR)…

    • 1390 Words
    • 6 Pages
    Improved Essays
  • Improved Essays

    The plot of this book was well structured with the authors delivering educative facts about what antibiotics are in general, the impacts they do have on diseases such as tuberculosis, bacterial pneumonia and how they make surgery and cancer chemotherapy safe. They continue to further educate their readers about the early days research to discover antibiotics from the soil to how they accidentally discovered the penicillin in the lab and how widely it got known during the global war era. ‘Thanks to PENICILLIN…he will come home’ was written on a famous poster during the war. After the discovery of antibiotics, little did we know that for the fact that the microbes have been around way before humans and plants existed, the resistance to antibiotics would emerge even after the misuse in humans, agriculture and…

    • 547 Words
    • 3 Pages
    Improved Essays
  • Improved Essays

    S. Aureus (MRSA)

    • 711 Words
    • 3 Pages

    Since the development of penicillin, countless lives have been saved over the years but over-prescribing and misuse of the medication has played a large role in the antibiotic resistance crisis. As a result, resistant strains of S. aureus have grown and spread into the community, some even showing resistance to multiple antibiotics (Ventola, 2015). Prior to the discovery of penicillin, death due to bacterial infections was quite common. When penicillin was first introduced to the public in the 1940's, it was found to be very effective at curing bacterial illnesses and also played an immense role in controlling infections during WWII. 10 years after it's introduction to the public, the first case of penicillin resistant S. aureus was…

    • 711 Words
    • 3 Pages
    Improved Essays
  • Improved Essays

    The field of medicine although obtained remarkable progress in recent decades, infectious illnesses triggered by pathogenic harmful bacteria are still an important risk to public wellness globally (1). Great attention has been paid to the anti-microbial level of resistance due to deaths and death rate from illnesses triggered by proof bacteria(2). Klebsiella pneumoniae is a Gram-negative bacteria that can cause different kinds of medical care associated attacks, such as pneumonia, bladder attacks, blood vessels attacks, injure or surgical site attacks, and meningitis (3). Healthcare- and outbreak- associated stress kinds of K. pneumoniae that appear highly transmissible and have a tendency for an anti-microbial level of resistance (AMR) or virulence gene purchase are an increasing proportion of the K. pneumoniae varieties (4). K. pneumoniae acquire safe from current…

    • 708 Words
    • 3 Pages
    Improved Essays
  • Improved Essays

    2) What types of infection control interventions should hospitals be using in order to reduce antibiotic exposure? 3) Should resources and time be devoted to new antibiotics? The literature review following concentrates on answering the three questions stated…

    • 513 Words
    • 3 Pages
    Improved Essays
  • Decent Essays

    Antimicrobial resistance is a global problem and is causing a serious threat to the prevention and treatment of an increasing range of diseases. The misuse of antibiotics does not cause the resistance but affects the spread of resistance. Bacteria adapt, mutate and multiply rapidly, therefore the problem cannot be solved completely, but if correct procedures will be implemented, the process can be slowed down. Without the effective global action many standard medical treatments will fail, resulting in death or disability of individuals or will turn into high risk procedures. The problem creates a need for developing stronger antibiotics in the future, but it is not certain that it can be achieved, as new antibiotics are difficult to find and…

    • 132 Words
    • 1 Pages
    Decent Essays
  • Superior Essays

    Methicillin Case Study

    • 1519 Words
    • 7 Pages

    Impact of penicillin, novobiocin, and kanamycin on Staphylococcus aureus bacterial growth Introduction: In today’s world, bacteria are becoming more abundant and strong in terms of their resistance to antibiotics. As a result of increasing prescription potency, clinicians are supposed to be conscious of those patients who are more inclined to infection by prescribing the appropriate antibiotics on the basis of their sensitivities along with their cultures (Fleming et al., 2006). A recent case study by Fleming and his colleagues showed the presence of methicillin-resistant Staphylococcus aureas (MRSA), a strain of Staphylococcus aureas that has relatively strong antibiotic resistance as a result of natural selection. Accordingly, they found…

    • 1519 Words
    • 7 Pages
    Superior Essays
  • Improved Essays

    Cat Scratch Disease

    • 1273 Words
    • 6 Pages

    However, in light of increasing antibiotic resistance by many bacteria, it may not be too long before current antibiotic treatment may not help. Further studies on this complex bacteria are needed in order to find different treatment options for patients in the future. Bibliography Braunwald E, Fauci AS, Isselbacher KJ, Martin JB, Petersdorf RG, Wilson JD (1987). Harrison’s Principles of Internal Medicine. 11th Edition.…

    • 1273 Words
    • 6 Pages
    Improved Essays
  • Improved Essays

    Why Germs Are Bad

    • 815 Words
    • 4 Pages

    Germs are everywhere. Fortunately, most pose no risks to people. And those that do cause disease usually can be killed with antibiotic drugs. Sometimes, however, harmful bacteria evolve ways to “laugh at” antibiotics — survive as if the poisons were not even there. This so-called drug resistance make infections hard, if not impossible, to treat.…

    • 815 Words
    • 4 Pages
    Improved Essays
  • Great Essays

    Like bacteria, bacteriophages can undergo mutations as well, evolving into stronger viruses. Also, phage resistance can be slowed down if infections are treated with a mixture of multiple different bacteriophages, or even in a mixture with antibiotics. With all of these advantages, bacteriophage therapy is a very “promising” solution in treating bacterial…

    • 1932 Words
    • 8 Pages
    Great Essays
  • Superior Essays

    This program promotes the appropriate use of antibiotics, improves patient outcomes, decreases the spread of infections due to resistance, and also reducing resistance as a whole. Partnering with the American Hospital Association, APIC has put together a toolkit with items like patient, hospital, and clinician resources available through a link in order to help inform people about the appropriate use of antibiotics. APIC even has an entire program dedicated to reducing the effects of resistant Clostridium…

    • 1274 Words
    • 6 Pages
    Superior Essays
  • Improved Essays

    Dalise Atwell BIO 212 Dr. Boles Excelsior College Penicillin and its Impact on Microbiology Penicillin has saved many lives past and current. “Before the discovery and use of penicillin, infectious diseases had been the leading cause of death throughout history. Furthermore, the therapeutic tools available for treating infections were few and of limited use. ”(Kardos 2011) Penicillin has been the drug of choice when treating many diseases.…

    • 1218 Words
    • 5 Pages
    Improved Essays
  • Improved Essays

    For more than 70 years, antibiotics have been used to treat bacterial infections of the body. The first appearance of this life changing medicine, was in the 1940’s on the battlefield. This medicine was named penicillin, the drug saved many from the brink of death, by fighting bacterial diseases; from then on antibiotics changed the face of medicine. Infection was no longer an impregnable wall that had to be broken down before the real treatment could begin, infections could be treated on site, at moments notice. As time passed, the world became co-dependent on the use of antibiotics to treat all of the body 's infections, and was repeatedly misused.…

    • 772 Words
    • 4 Pages
    Improved Essays
  • Great Essays

    Since the 1940,s, antimicrobial drugs, such as antibiotics, have been effectively used to cure patients with infectious diseases. Over time, however, many pathogens have evolved to resist the drugs that were designed to destroy them, making the products increasingly ineffective. This happens because the bacteria adapt to the environment due to natural selection. Then bacteria with the resistant genotype will reproduce and spread. Drug resistant pathogens are linked with the over prescription of antibiotics, as well as missing doses when taking antibiotics.[28]…

    • 1222 Words
    • 5 Pages
    Great Essays