Ewing's Sarcoma Theory

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Ewing’s sarcoma was first discovered by James Ewing in 1921 which he described as a “diffuse endothelioma of bone”. Ewing’s sarcoma is a highly aggressive bone cancer that is highly susceptible to radiation therapy.

There are two theories on the development of Ewing’s sarcoma; on one hand we have that these tumor arise from old primitive cells derived either from embryological tissue called neural crest. On the other hand, we have the theory that Ewing’s sarcoma arises from resident cells in the body (called mesenchymal stem cells). The treatment for ES have significant side effects since it is based of conventional chemotherapy; also radiation therapy works great against ES, All things considered side effects such as chronic swelling, joint

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