This novel route, have several characteristics to distinguish them from the more traditional target specific route available. The difference between normal skin and the lip skin. The labial skin on our lips looks clearly different from the rest of our body [38]. That is because it is much thinner in comparison to normal skin. Skin is divided in three separate layers - the stratum corneum, the epidermis and the dermis [39]. The protective stratum corneum is the outer layer that we can see, the epidermis is the layer of skin underneath it, and the dermis is the lowermost layer [40]. The cells of the stratum corneum are basically dead, and they protect the body from the harsh outer environment [41]. The epidermis is mostly responsible for producing
