The full name of EHBP1 is "EH domain binding protein 1." The symbol for the gene is EHBP1. Other names for the EHBP1 gene are HPC12, NASCIN, and KIAA0903. EH Domain Binding Protein 1 is a protein coding gene. This gene codes for an Eps15 homology domain binding protein. Its protein type is a vesicle. The encoded protein may play a role in endocytic trafficking. It is associated with prostate cancer. This gene is commonly found within the cytosol and the plasma membrane of a cell. It's size is 1231 amino acids long. Its cytogenetic location is on the short, or p, arm of chromosome 2 at position 15, or 2p15, located from base pair 62,673,850 to base pair 63,046,486. Ishikawa Nagase and other scientists, in 1998, cloned a partial EHBP1 cDNA, which
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Its causes are not fully known, but the gene is associated with the cancer. The overexpression of EHBP1 disrupts the cortical actin structures, and the depletion of EHBP1 inhibits endocytosis. EHBP1 interacts with P-Rex1, a protein that functions in guanine nucleotide exchange. P-Rex1 has been implicated in the spreading of cancer. EHBP1 proteins have been linked to PCa, or prostate cancer, but the details of the gene's involvement are still being researched. EHBP1 is primarily known as a marker for prostate cancer. EHBP1 is involved in the proper functioning of nuclear AKt, a protein kinase that is involved in apoptosis. A change in EHBP1 may cause issues with apoptosis, which can lead to a tumor. The type of cancer associated with defects or variations in the EHBP1 gene is prostate cancer. The type of prostate cancer is called, "Prostate Cancer, Hereditary, 12." EHBP1 is associated with a familial predisposition for an aggressive cancer of the prostate. The prostate is a gland in males that can be found around the urethra. The prostate helps produce semen, which is the liquid sperm can be found in. Prostate cancer is a common disease that typically affects middle aged or …show more content…
The early stages of prostate cancer usually do not produce noticeable symptoms. Men are often diagnosed after health screenings, such as a blood test for a substance called prostate specific antigen, or PSA, or from a rectal exam. As the tumor expands, signs and symptoms can include difficulty controlling the flow of urine, a feeling of not being able to completely empty the bladder, bloody semen or urine, or pain during ejaculation. However, these changes can also occur with many other genitourinary conditions, and one does not necessarily have prostate cancer if one or more symptoms occur. The severity and results of prostate cancer may vary, depending on the time the cancer was found and the time of formation. Early-stage prostate cancer can typically be treated successfully, and older men may have prostate tumors that grow so slowly that they may never cause health issues and may never require treatment. Other men may have much more aggressive cancer, which can be life-threatening. EHBP1 is a marker for an aggressive form of hereditary prostate cancer. Some cancerous tumors can invade nearby tissue and spread through the body. A tumor that spreads is called a metastatic cancer. The signs and symptoms of metastatic cancer depend on where it has
Its causes are not fully known, but the gene is associated with the cancer. The overexpression of EHBP1 disrupts the cortical actin structures, and the depletion of EHBP1 inhibits endocytosis. EHBP1 interacts with P-Rex1, a protein that functions in guanine nucleotide exchange. P-Rex1 has been implicated in the spreading of cancer. EHBP1 proteins have been linked to PCa, or prostate cancer, but the details of the gene's involvement are still being researched. EHBP1 is primarily known as a marker for prostate cancer. EHBP1 is involved in the proper functioning of nuclear AKt, a protein kinase that is involved in apoptosis. A change in EHBP1 may cause issues with apoptosis, which can lead to a tumor. The type of cancer associated with defects or variations in the EHBP1 gene is prostate cancer. The type of prostate cancer is called, "Prostate Cancer, Hereditary, 12." EHBP1 is associated with a familial predisposition for an aggressive cancer of the prostate. The prostate is a gland in males that can be found around the urethra. The prostate helps produce semen, which is the liquid sperm can be found in. Prostate cancer is a common disease that typically affects middle aged or …show more content…
The early stages of prostate cancer usually do not produce noticeable symptoms. Men are often diagnosed after health screenings, such as a blood test for a substance called prostate specific antigen, or PSA, or from a rectal exam. As the tumor expands, signs and symptoms can include difficulty controlling the flow of urine, a feeling of not being able to completely empty the bladder, bloody semen or urine, or pain during ejaculation. However, these changes can also occur with many other genitourinary conditions, and one does not necessarily have prostate cancer if one or more symptoms occur. The severity and results of prostate cancer may vary, depending on the time the cancer was found and the time of formation. Early-stage prostate cancer can typically be treated successfully, and older men may have prostate tumors that grow so slowly that they may never cause health issues and may never require treatment. Other men may have much more aggressive cancer, which can be life-threatening. EHBP1 is a marker for an aggressive form of hereditary prostate cancer. Some cancerous tumors can invade nearby tissue and spread through the body. A tumor that spreads is called a metastatic cancer. The signs and symptoms of metastatic cancer depend on where it has