Dextrometorphan
Introduction : State of importance Widespread of DXM use as an over-the-counter drug abuse.
Body : Discussion
History
The FDA approved DXM in 1958 in its legitimacy and effectiveness as a cough suppressant after researching. Afterwards, DXM, under the name “Romilar” was introduced as an OTC medication. However, in 1975, many teenagers abuse DXM, and Romilar was removed from the OTC market as a result (Shulgin, 1975). However, DXM was excluded from the Controlled Substances Act (CSA) of 1970; consequently, it was legal in producing and using; as a result, companies began introducing refined DXM products (e.g., Robitussin, Vicks-44, Dextrotussion) instead to limit recreational use by creating an unpleasant taste if consumed in mega dose. However, within a short time, those same manufactures began to produce forms of DXM with "appealing flavoring" which led to repeated recreational abuse (Shulgin, 1975). Prevalence of DXM cannot be estimated; consequently, the extent of DXM abuse cannot be measured. Nevertheless, recreational abuse has caused …show more content…
Acute megadoses of the drug generate psychological and physiologic effects similar to those of phencyclidine and Ketamine such as dissociative effect, delusion and hallucination, paranoia, agitation, hyperactive behavior, lack of muscle coordination, slurred speech, sweating and effect usually lasts approximately for six hours (Schwartz, 2005). Also, a false-positive screening test for phencyclidine in a urine test is the effect of megadose of DXM. DXM, as used in a recreational purpose, can cause addiction, including tolerance, withdrawal effect (Desai et al, 2006). Concerning about tolerance, it can lead to life-threatening effects at higher doses to produce same effect. Also, intoxication of DXM produces dissociation, and withdrawal is manifested by a profound depression (Miller,
Introduction : State of importance Widespread of DXM use as an over-the-counter drug abuse.
Body : Discussion
History
The FDA approved DXM in 1958 in its legitimacy and effectiveness as a cough suppressant after researching. Afterwards, DXM, under the name “Romilar” was introduced as an OTC medication. However, in 1975, many teenagers abuse DXM, and Romilar was removed from the OTC market as a result (Shulgin, 1975). However, DXM was excluded from the Controlled Substances Act (CSA) of 1970; consequently, it was legal in producing and using; as a result, companies began introducing refined DXM products (e.g., Robitussin, Vicks-44, Dextrotussion) instead to limit recreational use by creating an unpleasant taste if consumed in mega dose. However, within a short time, those same manufactures began to produce forms of DXM with "appealing flavoring" which led to repeated recreational abuse (Shulgin, 1975). Prevalence of DXM cannot be estimated; consequently, the extent of DXM abuse cannot be measured. Nevertheless, recreational abuse has caused …show more content…
Acute megadoses of the drug generate psychological and physiologic effects similar to those of phencyclidine and Ketamine such as dissociative effect, delusion and hallucination, paranoia, agitation, hyperactive behavior, lack of muscle coordination, slurred speech, sweating and effect usually lasts approximately for six hours (Schwartz, 2005). Also, a false-positive screening test for phencyclidine in a urine test is the effect of megadose of DXM. DXM, as used in a recreational purpose, can cause addiction, including tolerance, withdrawal effect (Desai et al, 2006). Concerning about tolerance, it can lead to life-threatening effects at higher doses to produce same effect. Also, intoxication of DXM produces dissociation, and withdrawal is manifested by a profound depression (Miller,