The Cause and Effect of Mutations on the Cystic Fibrosis Transmembrane Conductance Regulator Gene and How it Affects Lung Functions in an Individual
Sterling Wood
Biology 2458 Section 005, Pankaj B.C., October 11, 2015
Introduction
Many people do not realize all the different factors that are a necessity when it comes to just breathing. The air we breathe is filled with many different particles and bacteria that could cause major problems if they were to reach the alveoli. With that being said, the human body devised ways to inhibit this by the lungs secreting a sticky mucous layer throughout the airways that traps the particles and bacteria. The cilia of the lungs then recycle the mucous by moving it out of the airways and into the throat …show more content…
Also if you notice that a baby’s skin is salty when you kiss them, then their “sweat electrolyte levels” (Davies et al. 2007) should be measured to see if they are too high. If they happen to be too high this is normally a pretty good sign that they have Cystic Fibrosis although, this test is not always accurate in determining wither or not a child has this horrible disease. On the other hand, most signs and symptoms don’t begin to arise until the child is older. Normal symptoms include coughing up blood filled phlegm, “recurrent bronchial infection” (Hopkin 1991) and “progressive bronchiectasis” (Hopkin 1991) both of which normally occur from the “bacterium called Pseudomonas aeruginosa” (Christensen 2002) due to their in ability to expel the mucous. In addition to this many people with Cystic Fibrosis also normally experience “excessive inflammatory response to pathogens” (Davies et al. 2007). With regards to what was stated above, there are several different ways to diagnosis cystic fibrosis when you first begin to notice these
Sterling Wood
Biology 2458 Section 005, Pankaj B.C., October 11, 2015
Introduction
Many people do not realize all the different factors that are a necessity when it comes to just breathing. The air we breathe is filled with many different particles and bacteria that could cause major problems if they were to reach the alveoli. With that being said, the human body devised ways to inhibit this by the lungs secreting a sticky mucous layer throughout the airways that traps the particles and bacteria. The cilia of the lungs then recycle the mucous by moving it out of the airways and into the throat …show more content…
Also if you notice that a baby’s skin is salty when you kiss them, then their “sweat electrolyte levels” (Davies et al. 2007) should be measured to see if they are too high. If they happen to be too high this is normally a pretty good sign that they have Cystic Fibrosis although, this test is not always accurate in determining wither or not a child has this horrible disease. On the other hand, most signs and symptoms don’t begin to arise until the child is older. Normal symptoms include coughing up blood filled phlegm, “recurrent bronchial infection” (Hopkin 1991) and “progressive bronchiectasis” (Hopkin 1991) both of which normally occur from the “bacterium called Pseudomonas aeruginosa” (Christensen 2002) due to their in ability to expel the mucous. In addition to this many people with Cystic Fibrosis also normally experience “excessive inflammatory response to pathogens” (Davies et al. 2007). With regards to what was stated above, there are several different ways to diagnosis cystic fibrosis when you first begin to notice these