Having killed over one-third of the affected populations, the plague spread to selected individuals. Mainly affecting weak individuals with a history of mental stress or elderly, the Black Death arose many questions surrounding the factors that affected frailty gene patterns. The Black Death was the most catastrophic epidemic to ever sweep over the Western Hemisphere during the fourteenth century, but the plague’s aftermath might have proved beneficial to the survival rate and natural selection of frailty level ratings.
The full extent of the Black Death’s geographical origins is still uncertain. The earliest recorded evidence of the plague’s presence dates back to the year 1346 in cities of the Kipchak Khanate of the Golden Hord. It lasted roughly seven years from its …show more content…
On examining deceased individuals from London’s East Smithfield Black Death cemetery, victims of the plague indicated that the pandemic targeted older adults and elders versus their younger counterparts. Upon further examination of markings on the skeletons of those who were subjected to physiological stressors, research also revealed that individuals already in poor health experienced increased risk of death by the bubonic plague. These physiological stressors often included short stature or porotic hyperostosis that left stress markings on the skeleton. Given its high death rate, it is generally assumed that the plague killed arbitrarily, but the research gives reason to believe the Black Death, like any other cause, was selective. The epidemic might have changed health and demographics in the survivors, affecting genetic variations. It could have represented an act of natural selection, weeding out the frail