Then, that group received the placebo injections in the opposite. Rats that had received the ethanol in the designated room became more tolerant to the hypothermic effects after numerous injections. Meanwhile, there was a large hypothermic response in the rats that received the ethanol in a different environment from the one where they had previously received the numerous doses of ethanol. People hear tolerance and they immediately assume it refers to a diminished experience of some drug effect after numerous doses of a drug. Prior to this class, dose tolerance was the only form of tolerance I had learned about. Not only is there tolerance to drug effects, but there is conditioned withdrawl and tolerance depending on environment; as seen in this study. Lastly, in this experiment the rats both received the same amount of ethanol doses but their response to the drug varied depending on if they were in a familiar or unfamiliar
Then, that group received the placebo injections in the opposite. Rats that had received the ethanol in the designated room became more tolerant to the hypothermic effects after numerous injections. Meanwhile, there was a large hypothermic response in the rats that received the ethanol in a different environment from the one where they had previously received the numerous doses of ethanol. People hear tolerance and they immediately assume it refers to a diminished experience of some drug effect after numerous doses of a drug. Prior to this class, dose tolerance was the only form of tolerance I had learned about. Not only is there tolerance to drug effects, but there is conditioned withdrawl and tolerance depending on environment; as seen in this study. Lastly, in this experiment the rats both received the same amount of ethanol doses but their response to the drug varied depending on if they were in a familiar or unfamiliar