Cocaine Description And Analysis

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Cocaine is a stimulant, addictive and illicit drug. It is the second drug after cannabis in the number of seizures globally. The global seizures in 2012 were 671 tones. In Europe, 14.1 million or (4.2%) of adults are estimated to have been taking cocaine in their life time according to the European monitoring centre for drugs and drug addiction (EMCDDA). Cocaine and its metabolites can be detected in hair, urine, saliva and blood1. It can be also be detected in surface water, waste water treatment plants2 and in banknotes3. Different methods have been reported for cocaine detection; enzyme immunoassay3, 4, 5, 6 , gas chromatography (GC) and liquid chromatography (LC), capillary electrophoresis (CE), immunoassay, thermal desorption tandem mass spectrometry (TD-MS2) and ion-mobility spectrometry (IMS)3. …show more content…
It has been used in detecting and quantifying specific antibodies and antigens in different samples7. ELISA has the advantages of high sensitivity and strong specificity due of the selectivity and affinity of monoclonal antibodies. Competitive ELISA is used for detection of the small molecules and for its high sensitivity. Electrochemical immunosensor combines the advantages of immunoassay and electrochemical detection. Electrochemical detection has the advantages of miniaturization, simple instrumentations, low cost, portable and

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