Clostridium Tetanus: A Pathogenic Disease

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Tetanus is a pathogenic disease caused by the bacterium, Clostridium tetani , which affects the nervous system. It is an obligate anaerobe, resistant endospore-forming (protective coat), gram-positive bacilli, and motile by peritrichous flagella. Traces of C. tetani have been found in soil, street dust, rusty nail, and animal feces. When the pathogen gains access into the body, either from deep lesions or cuts , a deadly neurotoxin called tetanospasmin spreads through the bloodstream reaching the peripheral nerves and blocking the release of inhibitory neurotransmitters across the synaptic terminal. The continuous stimulation by an excitatory neurotransmitter, leads to muscle spasms primarily starting with the muscles of the jaw hence, the

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