The combination of the medications in the chemo regiment known as RICE, stand for the medications, Rituximab, Ifosfamide, Carboplaten, and Etoposide.
-Rituximab: monoclonal antibodies, helping the body’s immune system to destroy the cancer cells.
-Ifosfamide: alkylating agent, chemotherapy agent, stopping the cancer cells from dividing.
- Carboplatin: alkylating agent, chemotherapy agent, stopping the cancer cells from dividing.
-Etoposide: plant alkaloid, chemotherapy agent, cell cycle specific.
How would you explain to your patient the rationale for why they are receiving combination therapy (cytotoxic chemotherapy plus monoclonal antibody/targeted therapy) at a level the patient would understand? …show more content…
Each one does a different job and together they are more successful in destroying the cancer cells. A cancer cell, is a cell that stopped working properly and does not stop dividing, like a normal cell does. The chemotherapy drugs, Ifosfamide and Carboplatin, stops the cancer cells from dividing. The medication Rituximab works by helping your body’s immune system destroy the cancer cells. The chemotherapy agent, Etoposide, kills the cancer cells when they are in a specific cycle of the cell dividing. You have heard the discussion on how our bodies can grow resistant to antibiotics. The same is true to chemotherapy agents. And when combining different treatments together, the chance for the cancer cells to become resistant to the chemotherapy is less likely. Also by combining the different chemotherapies, they each are more effective than if they would be given