Celiac Disease Research Paper

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Celiac disease (CD) AKA celiac sprue, is a auto immune disorder of the small intestine. CD affects genetically predisposed individuals when they ingest the protein gluten. Gluten is a storage protein that is necessary for the germination of grains including; wheat, rye, barley, and to some degree, oats.When a patient with CD ingests gluten the immune system's response damages the intestinal lining mucosa through lymphocytosis, crypt hyperplasia and villous atrophy. These changes are the hallmarks of the disease and they need to be present to make a diagnosis of CD.
Unfortunately its clinical presentation varies from the classical malabsorption symptoms with diarrhea, anemia, vitamin deficiency, abdominal distension or failure to thrive in children, to a less classic presentation characterized by nonspecific fatigue.
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There are 300 known symptoms which could Indicate CD. While only one out of every 100 people have CD, approximately one out of seven are properly diagnosed with CD. Some people with CD have no symptoms at all. However, as Larry Studt, M.D. stated “people with celiac disease are still at risk for long-term complications, whether or not they display any symptoms”.Left untreated, celiac disease can lead to additional serious health problems such as; Type I diabetes and multiple sclerosis (MS), dermatitis herpetiformis, anemia, osteoporosis, infertility and miscarriage, neurological conditions like epilepsy and migraines, short stature, intestinal and esophageal

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